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老年时期使用非法及合法物质进行兴奋剂使用行为

[Doping with illegal and legal substances in old age].

作者信息

Münzer Thomas

机构信息

Geriatrische Klinik St. Gallen, Rorschacherstr. 94, 9000, St. Gallen, Schweiz.

出版信息

Z Gerontol Geriatr. 2018 Feb;51(2):149-151. doi: 10.1007/s00391-017-1350-z. Epub 2018 Jan 5.

DOI:10.1007/s00391-017-1350-z
PMID:29305652
Abstract

The number of old persons who participate in sports and can even achieve peak performances is increasing steadily. Normal aging, however, is associated with decreased muscle strength and a decline in cardiovascular endurance even in those persons who regularly participate in sports. Thus, it seems obvious to impact on muscle mass and muscle strength by using anabolic substances. The number of older persons who illegally use doping substances is currently unknown. Besides classical anabolic drugs, other proteins and amino acids are used to impact on muscle mass or strength. This article provides some insights into clinical trials of classical anabolic drugs in older persons and gives an overview on more recent studies examining the potential effects of taurine, creatine and whey protein in older persons.

摘要

参加体育活动甚至能达到最佳表现的老年人数量正在稳步增加。然而,即使是那些经常参加体育活动的人,正常衰老也与肌肉力量下降和心血管耐力降低有关。因此,使用合成代谢物质来影响肌肉质量和肌肉力量似乎是显而易见的。目前尚不清楚非法使用兴奋剂的老年人数量。除了传统的合成代谢药物外,其他蛋白质和氨基酸也被用于影响肌肉质量或力量。本文提供了一些关于传统合成代谢药物在老年人中的临床试验的见解,并概述了最近关于牛磺酸、肌酸和乳清蛋白对老年人潜在影响的研究。

相似文献

1
[Doping with illegal and legal substances in old age].老年时期使用非法及合法物质进行兴奋剂使用行为
Z Gerontol Geriatr. 2018 Feb;51(2):149-151. doi: 10.1007/s00391-017-1350-z. Epub 2018 Jan 5.
2
[Daily doping. Higher, faster, stronger].[每日兴奋剂。更高、更快、更强]
Krankenpfl Soins Infirm. 2012;105(2):40-3, 62-5.
3
Effect of creatine supplementation and drop-set resistance training in untrained aging adults.补充肌酸和递减组抗阻训练对未经训练的老年成年人的影响。
Exp Gerontol. 2016 Oct;83:112-9. doi: 10.1016/j.exger.2016.08.005. Epub 2016 Aug 11.
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The sports psychiatrist and performance-enhancing drugs.运动精神科医生与提高成绩的药物。
Int Rev Psychiatry. 2016 Dec;28(6):564-571. doi: 10.1080/09540261.2016.1190690. Epub 2016 Jun 16.
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Performance-enhancing substances in adolescent athletes.青少年运动员使用的提高成绩的物质。
Tex Med. 2002 Feb;98(2):41-6.
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Bodybuilders' accounts of synthol use: The construction of lay expertise online.健美运动员关于使用合成代谢类固醇的说法:在线外行专业知识的构建。
J Health Psychol. 2016 Sep;21(9):1939-48. doi: 10.1177/1359105314568579. Epub 2015 Feb 2.
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Creatine co-ingestion with carbohydrate or cinnamon extract provides no added benefit to anaerobic performance.同时摄入肌酸与碳水化合物或肉桂提取物对无氧运动表现并无额外益处。
Eur J Sport Sci. 2016 Sep;16(6):685-93. doi: 10.1080/17461391.2015.1071877. Epub 2015 Aug 27.
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[Brain doping. With smart pills becoming the perfect human being].
Krankenpfl Soins Infirm. 2012;105(2):10-3.
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[Increase of muscle mass and strength with hormones and other drugs, combined with physical training].
Orv Hetil. 2007 Mar 11;148(10):451-6. doi: 10.1556/OH.2007.27793.
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Effects of amino acid derivatives on physical, mental, and physiological activities.氨基酸衍生物对身体、心理和生理活动的影响。
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本文引用的文献

1
[Anabolic and molecular interventions on muscle : Meaningful anti-aging strategy?].[对肌肉的合成代谢和分子干预:有意义的抗衰老策略?]
Z Gerontol Geriatr. 2017 Dec;50(8):693-696. doi: 10.1007/s00391-017-1299-y. Epub 2017 Aug 14.
2
A whey protein-based multi-ingredient nutritional supplement stimulates gains in lean body mass and strength in healthy older men: A randomized controlled trial.一项基于乳清蛋白的多成分营养补充剂对健康老年男性瘦体重和力量增长的刺激作用:一项随机对照试验。
PLoS One. 2017 Jul 18;12(7):e0181387. doi: 10.1371/journal.pone.0181387. eCollection 2017.
3
Association of Testosterone Levels With Anemia in Older Men: A Controlled Clinical Trial.
老年男性睾酮水平与贫血的关联:一项对照临床试验。
JAMA Intern Med. 2017 Apr 1;177(4):480-490. doi: 10.1001/jamainternmed.2016.9540.
4
Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets.血浆牛磺酸、糖尿病遗传易感性以及减肥饮食对胰岛素敏感性的影响
J Clin Endocrinol Metab. 2016 Oct;101(10):3820-3826. doi: 10.1210/jc.2016-1760. Epub 2016 Jul 28.
5
Ingestion of Wheat Protein Increases In Vivo Muscle Protein Synthesis Rates in Healthy Older Men in a Randomized Trial.一项随机试验表明,健康老年男性摄入小麦蛋白可提高体内肌肉蛋白合成率。
J Nutr. 2016 Sep;146(9):1651-9. doi: 10.3945/jn.116.231340. Epub 2016 Jul 20.
6
Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly.运动联合乳清蛋白、氨基酸和维生素 D 补充剂可增加去脂体重和力量、功能以及生活质量,减轻老年肌少症患者的炎症。
Am J Clin Nutr. 2016 Mar;103(3):830-40. doi: 10.3945/ajcn.115.113357. Epub 2016 Feb 10.
7
Effects of long-term low-dose dietary creatine supplementation in older women.长期低剂量膳食补充肌酸对老年女性的影响。
Exp Gerontol. 2015 Oct;70:97-104. doi: 10.1016/j.exger.2015.07.012. Epub 2015 Jul 17.
8
Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.维生素D和富含亮氨酸的乳清蛋白营养补充剂对老年人肌肉减少症指标的影响,PROVIDE研究:一项随机、双盲、安慰剂对照试验。
J Am Med Dir Assoc. 2015 Sep 1;16(9):740-7. doi: 10.1016/j.jamda.2015.05.021. Epub 2015 Jul 10.
9
Danazol therapy for the anemia of myelofibrosis: assessment of efficacy with current criteria of response and long-term results.达那唑治疗骨髓纤维化贫血:依据当前疗效标准及长期结果评估疗效
Ann Hematol. 2015 Nov;94(11):1791-6. doi: 10.1007/s00277-015-2435-7. Epub 2015 Jun 28.
10
Effect of oral taurine on morbidity and mortality in elderly hip fracture patients: a randomized trial.口服牛磺酸对老年髋部骨折患者发病率和死亡率的影响:一项随机试验。
Int J Mol Sci. 2015 May 29;16(6):12288-306. doi: 10.3390/ijms160612288.