Münzer Thomas
Geriatrische Klinik St. Gallen, Rorschacherstr. 94, 9000, St. Gallen, Schweiz.
Z Gerontol Geriatr. 2018 Feb;51(2):149-151. doi: 10.1007/s00391-017-1350-z. Epub 2018 Jan 5.
The number of old persons who participate in sports and can even achieve peak performances is increasing steadily. Normal aging, however, is associated with decreased muscle strength and a decline in cardiovascular endurance even in those persons who regularly participate in sports. Thus, it seems obvious to impact on muscle mass and muscle strength by using anabolic substances. The number of older persons who illegally use doping substances is currently unknown. Besides classical anabolic drugs, other proteins and amino acids are used to impact on muscle mass or strength. This article provides some insights into clinical trials of classical anabolic drugs in older persons and gives an overview on more recent studies examining the potential effects of taurine, creatine and whey protein in older persons.
参加体育活动甚至能达到最佳表现的老年人数量正在稳步增加。然而,即使是那些经常参加体育活动的人,正常衰老也与肌肉力量下降和心血管耐力降低有关。因此,使用合成代谢物质来影响肌肉质量和肌肉力量似乎是显而易见的。目前尚不清楚非法使用兴奋剂的老年人数量。除了传统的合成代谢药物外,其他蛋白质和氨基酸也被用于影响肌肉质量或力量。本文提供了一些关于传统合成代谢药物在老年人中的临床试验的见解,并概述了最近关于牛磺酸、肌酸和乳清蛋白对老年人潜在影响的研究。