Loughnan B A, King M J, Grundy E M, Young D L, Hall G M
Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Br J Anaesth. 1989 Mar;62(3):297-300. doi: 10.1093/bja/62.3.297.
We studied the effects of supplementing anaesthesia with halothane (up to 1.5%, inspired) on the somatosensory evoked potential recorded in the extradural space of six patients before corrective surgery for idiopathic adolescent scoliosis. A further six patients in whom anaesthesia was supplemented with thiopentone acted as a control group. Halothane 1.5% resulted in a significant decrease in overall amplitude (P less than 0.05) from the left leg only. Halothane had no significant effect on overall amplitude, first peak amplitude, second peak amplitude and first peak latency. We conclude that halothane is unlikely to alter the interpretation of somatosensory evoked potentials recorded extradurally during scoliosis surgery. A possible unilateral effect of halothane on the concave side in idiopathic adolescent scoliosis needs further investigation.
我们研究了在特发性青少年脊柱侧弯矫正手术前，使用氟烷（吸入浓度高达1.5%）辅助麻醉对6例患者硬膜外记录的体感诱发电位的影响。另外6例使用硫喷妥钠辅助麻醉的患者作为对照组。1.5%的氟烷仅导致左腿的总体波幅显著降低（P<0.05）。氟烷对总体波幅、第一峰波幅、第二峰波幅和第一峰潜伏期无显著影响。我们得出结论，氟烷不太可能改变脊柱侧弯手术期间硬膜外记录的体感诱发电位的解读。氟烷对特发性青少年脊柱侧弯凹侧可能存在的单侧效应需要进一步研究。
