Loughnan B A, Yau K W, Ransford A O, Hall G M
Department of Anaesthetics, Royal National Orthopaedic Hospital, Stanmore, Middlesex, London.
Anaesthesia. 1991 Nov;46(11):912-4. doi: 10.1111/j.1365-2044.1991.tb09844.x.
We have studied the effects of the epidural administration of diamorphine 0.1 mg/kg at the L3-4 interspace on somatosensory evoked potentials in the cervical epidural space before corrective surgery for idiopathic adolescent scoliosis. A further eight patients in whom anaesthesia was maintained with a propofol infusion acted as a control group. Epidural diamorphine had no effect on the latency or amplitude of the evoked potentials. We conclude that epidural diamorphine is a suitable technique to use in scoliosis surgery because of its lack of effect on neurophysiological variables, although the potential respiratory problems need investigation.
我们研究了在特发性青少年脊柱侧弯矫正手术前，于L3 - 4间隙硬膜外注射0.1 mg/kg海洛因对颈段硬膜外间隙体感诱发电位的影响。另外8例以丙泊酚输注维持麻醉的患者作为对照组。硬膜外注射海洛因对诱发电位的潜伏期或波幅没有影响。我们得出结论，硬膜外注射海洛因是脊柱侧弯手术中一种合适的技术，因为它对神经生理变量没有影响，尽管潜在的呼吸问题需要进一步研究。
