Marchesi Maria Chiara, Timpano Cecilia Carlotta, Busechian Sara, Pieramati Camillo, Rueca Fabrizio
Dipartimento di Medicina Veterinaria, Università degli Studi di Perugia, Perugia, Italy.
Vet Ital. 2017 Dec 29;53(4):309-313. doi: 10.12834/VetIt.903.4608.1.
Endoscopy is a common, minimally invasive diagnostic technique that can be used to observe internal organs, e.g. the stomach, and to obtain mucosal bioptic samples for histo pathological examination. The aim of this study was to analyse the concordance between endoscopic and histological evaluation of gastric diseases in dogs. One hundred twenty-nine medical records of dogs undergoing gastroscopy have been received and stored by the Veterinary Hospital of Perugia University (Perugia, Italy) between 2009-2012. The concordance between endoscopic and histological reports of acute and chronic gastritis or gastric tumours was assessed by Cohen's k coe cient. Considering histological diagnosis as the "gold standard", sensitivity, speci city, positive predictive value (PPV), and negative predictive value (NPV) of the endoscopic report have been calculated. Frequencies of gastritis types di ered between macroscopic and microscopic analyses. The evaluation of histological and endoscopic agreement was fair (0.35). Endoscopy showed sensitivity of 45%, 88%, and 100% for acute gastritis, chronic gastritis, and gastric tumours, respectively; and speci city of 84%, 71%, and 100%. The positive predictive value and NPV resulted to be 25% and 93% for acute gastritis, 93% and 60 % for chronic gastritis, 100% and 100% for gastric tumours. The results of this study show that gastric endoscopy cannot be performed as a screening exam, and that to optimise diagnosis both endoscopic and histological exam should be conducted.
内镜检查是一种常见的微创诊断技术，可用于观察内部器官，如胃，并获取黏膜活检样本进行组织病理学检查。本研究的目的是分析犬类胃病内镜检查与组织学评估之间的一致性。佩鲁贾大学兽医院（意大利佩鲁贾）在2009年至2012年期间接收并存储了129份接受胃镜检查的犬类病历。通过科恩k系数评估急性和慢性胃炎或胃肿瘤的内镜报告与组织学报告之间的一致性。以组织学诊断为“金标准”，计算内镜报告的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。胃炎类型的频率在宏观和微观分析之间存在差异。组织学和内镜一致性评估为中等（0.35）。内镜检查对急性胃炎、慢性胃炎和胃肿瘤的敏感性分别为45%、88%和100%；特异性分别为84%、71%和100%。急性胃炎的阳性预测值和NPV分别为25%和93%，慢性胃炎为93%和60%，胃肿瘤为100%和100%。本研究结果表明，胃内镜检查不能作为筛查检查进行，为优化诊断，应同时进行内镜检查和组织学检查。
