• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
The circadian clock in cardiovascular regulation and disease: Lessons from the Nobel Prize in Physiology or Medicine 2017.心血管调节与疾病中的生物钟：来自2017年诺贝尔生理学或医学奖的启示
Eur Heart J. 2018 Jun 21;39(24):2326-2329. doi: 10.1093/eurheartj/ehx775.
2
[Nobel Prize in Physiology or Medicine 2017. Our complex inner rhythms].[2017年诺贝尔生理学或医学奖。我们复杂的内在节律]
Medicina (B Aires). 2017;77(6):524-526.
3
[The 2017 Nobel prize in physiology and medicine for the circardian clock].[2017年诺贝尔生理学或医学奖授予生物钟研究]
Bull Cancer. 2017 Oct;104(10):821-822. doi: 10.1016/j.bulcan.2017.10.005.
4
Temporal partitioning of cardiac metabolism by the cardiomyocyte circadian clock.心肌细胞昼夜节律钟对心脏代谢的时间划分。
Exp Physiol. 2016 Aug 1;101(8):1035-9. doi: 10.1113/EP085779.
5
[Nobel time for the circadian clock - Nobel Prize in Medicine 2017: Jeffrey C. Hall, Michael Rosbash and Michael W. Young].[生物钟的诺贝尔奖时刻——2017年诺贝尔生理学或医学奖：杰弗里·C·霍尔、迈克尔·罗斯巴什和迈克尔·W·扬]
Med Sci (Paris). 2018 May;34(5):480-484. doi: 10.1051/medsci/20183405023. Epub 2018 Jun 13.
6
Physiology Flies with Time.生理学与时共进。
Cell. 2017 Nov 30;171(6):1232-1235. doi: 10.1016/j.cell.2017.11.028.
7
[The Circadian Clock is Now Ticking Even in Stockholm - Nobel Prize in Medicine 2017].即使在斯德哥尔摩，生物钟仍在滴答作响——2017年诺贝尔医学奖
Dtsch Med Wochenschr. 2017 Dec;142(25):1897-1900. doi: 10.1055/s-0043-122203. Epub 2017 Dec 14.
8
[Research advances in relationship between biological clock and cardiovascular diseases].[生物钟与心血管疾病关系的研究进展]
Sheng Li Xue Bao. 2019 Oct 25;71(5):783-791.
9
Mechanism of the circadian clock in physiology.生理节律钟的机制。
Am J Physiol Regul Integr Comp Physiol. 2013 Jun 15;304(12):R1053-64. doi: 10.1152/ajpregu.00066.2013. Epub 2013 Apr 10.
10
Medicine Nobel awarded for work on circadian clocks.诺贝尔医学奖授予在生物钟研究方面的工作成果。
Nature. 2017 Oct 2;550(7674):18. doi: 10.1038/nature.2017.22736.

引用本文的文献

1
Health risks and genetic architecture of objectively measured multidimensional sleep health.客观测量的多维睡眠健康的健康风险与遗传结构
Nat Commun. 2025 Jul 31;16(1):7026. doi: 10.1038/s41467-025-62338-0.
2
Electromagnetic dynamic stability analysis of power electronics-dominated systems using eigenstructure-preserved LTP Theory.基于特征结构保持LTP理论的电力电子主导系统电磁动态稳定性分析
Nat Commun. 2025 Jul 25;16(1):6852. doi: 10.1038/s41467-025-62183-1.
3
Role of circadian transcription factor REV-ERB in cardiovascular diseases: a review.昼夜节律转录因子REV-ERB在心血管疾病中的作用：综述
Front Cardiovasc Med. 2025 Apr 4;12:1516279. doi: 10.3389/fcvm.2025.1516279. eCollection 2025.
4
Health position paper and redox perspectives - Disease burden by transportation noise.健康立场文件和氧化还原观点——交通噪声导致的疾病负担。
Redox Biol. 2024 Feb;69:102995. doi: 10.1016/j.redox.2023.102995. Epub 2023 Dec 18.
5
Timing Matters: The Interplay between Early Mealtime, Circadian Rhythms, Gene Expression, Circadian Hormones, and Metabolism-A Narrative Review.时间很重要：早用餐时间、昼夜节律、基因表达、昼夜节律激素与新陈代谢之间的相互作用——一篇综述
Clocks Sleep. 2023 Sep 6;5(3):507-535. doi: 10.3390/clockssleep5030034.
6
Dynamic neuronal instability generates synaptic plasticity and behavior: Insights from Drosophila sleep.动态神经元不稳定性产生突触可塑性和行为：来自果蝇睡眠的见解。
Neurosci Res. 2024 Jan;198:1-7. doi: 10.1016/j.neures.2023.06.009. Epub 2023 Jun 28.
7
In-vitro antiplatelet effect of melatonin in healthy individuals and patients with type 2 diabetes mellitus.褪黑素对健康个体和 2 型糖尿病患者的体外抗血小板作用。
J Endocrinol Invest. 2023 Dec;46(12):2493-2500. doi: 10.1007/s40618-023-02102-7. Epub 2023 May 6.
8
Short-term and intermediate-term fine particulate air pollution are synergistically associated with habitual sleep variability in adolescents - A cross-sectional study.短期和中期细颗粒物空气污染与青少年习惯性睡眠变异性呈协同关联——一项横断面研究。
Environ Res. 2023 Jun 15;227:115726. doi: 10.1016/j.envres.2023.115726. Epub 2023 Mar 21.
9
Impact of the period of the day on all-cause mortality and major cardiovascular complications after arterial vascular surgeries.一天中不同时段对动脉血管手术后全因死亡率和主要心血管并发症的影响。
PLoS One. 2023 Jan 5;18(1):e0279873. doi: 10.1371/journal.pone.0279873. eCollection 2023.
10
Soil and water pollution and human health: what should cardiologists worry about?土壤和水污染与人类健康：心脏病学家应该担心什么？
Cardiovasc Res. 2023 Mar 31;119(2):440-449. doi: 10.1093/cvr/cvac082.

本文引用的文献

1
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.心脏手术围术期心肌损伤的日间变化及其通过 Rev-Erbα 拮抗作用的预防：一项单中心倾向匹配队列研究和一项随机研究。
Lancet. 2018 Jan 6;391(10115):59-69. doi: 10.1016/S0140-6736(17)32132-3. Epub 2017 Oct 26.
2
REV-ERBα ameliorates heart failure through transcription repression.REV-ERBα 通过转录抑制改善心力衰竭。
JCI Insight. 2017 Sep 7;2(17). doi: 10.1172/jci.insight.95177.
3
SCA1 Cells from the Heart Possess a Molecular Circadian Clock and Display Circadian Oscillations in Cellular Functions.心脏来源的 SCA1 细胞具有分子生物钟，并在细胞功能中显示出昼夜节律波动。
Stem Cell Reports. 2017 Sep 12;9(3):762-769. doi: 10.1016/j.stemcr.2017.07.010. Epub 2017 Aug 10.
4
Circadian networks in human embryonic stem cell-derived cardiomyocytes.人胚胎干细胞衍生心肌细胞中的昼夜节律网络。
EMBO Rep. 2017 Jul;18(7):1199-1212. doi: 10.15252/embr.201743897. Epub 2017 May 23.
5
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.破坏关键的昼夜节律调节因子CLOCK会导致年龄依赖性心血管疾病。
J Mol Cell Cardiol. 2017 Apr;105:24-37. doi: 10.1016/j.yjmcc.2017.01.008. Epub 2017 Feb 20.
6
Transcriptional architecture of the mammalian circadian clock.哺乳动物昼夜节律钟的转录结构
Nat Rev Genet. 2017 Mar;18(3):164-179. doi: 10.1038/nrg.2016.150. Epub 2016 Dec 19.
7
Temporal partitioning of cardiac metabolism by the cardiomyocyte circadian clock.心肌细胞昼夜节律钟对心脏代谢的时间划分。
Exp Physiol. 2016 Aug 1;101(8):1035-9. doi: 10.1113/EP085779.
8
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure.欧洲心脏病学会心脏细胞生物学工作组立场文件：缺血性心脏病和心力衰竭心肌修复与再生的细胞疗法
Eur Heart J. 2016 Jun 14;37(23):1789-98. doi: 10.1093/eurheartj/ehw113. Epub 2016 Apr 7.
9
Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology.心肌细胞生物钟对心脏生理和病理生理的影响。
J Biol Rhythms. 2015 Jun;30(3):183-205. doi: 10.1177/0748730415575246. Epub 2015 Mar 22.
10
Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.心肌细胞特异性的BMAL1在心脏的代谢、信号传导及收缩功能维持中发挥关键作用。
J Biol Rhythms. 2014 Aug;29(4):257-76. doi: 10.1177/0748730414543141.

The circadian clock in cardiovascular regulation and disease: Lessons from the Nobel Prize in Physiology or Medicine 2017.

作者信息

Van Laake Linda W, Lüscher Thomas F, Young Martin E

机构信息

Division of Heart and Lungs, Department of Cardiology and Regenerative Medicine Center, University Medical Center, Heideberglaan 100, CX Utrecht, the Netherlands.

Department of Cardiology, Royal Brompton & Harefield Hospitals and Imperial College, Sidney Street, London, UK.

出版信息

Eur Heart J. 2018 Jun 21;39(24):2326-2329. doi: 10.1093/eurheartj/ehx775.

DOI:10.1093/eurheartj/ehx775
PMID:29309706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6012474/
Abstract
摘要