Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, "Agia Sophia" Children's Hospital, Athens, Greece.
Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, "Agia Sophia" Children's Hospital, Athens, Greece.
Metabolism. 2018 Sep;86:145-153. doi: 10.1016/j.metabol.2017.12.016. Epub 2018 Jan 6.
Transition from pediatric to adult care for young women with Turner Syndrome (TS) is characterized by high drop-out rates and inadequate follow-up, leading to increased morbidity and mortality. The complexity of the health issues young women with TS face or new problems that may arise warrants a well-structured and efficiently coordinated gradual transition plan, which is adapted to the individual needs of the emerging young adult and is based on interdisciplinary communication between physicians. In order to achieve a high level of care, it is important for the patient to be sincerely informed about her condition but also supported throughout this critical period of rising responsibility and autonomy by an experienced, multidisciplinary team. In this review, we present the basic concepts that should characterize transition and the major health issues that should be thoroughly addressed, including growth, Hormone Replacement Treatment and fertility options, cardiovascular disease, bone health, gastrointestinal disorders, autoimmunity, orthopaedic and ENT issues, as well as the overall psychological well-being of the young adult with TS.
从儿科到特纳综合征（TS）成年期的过渡，其特征是高辍学率和随访不足，导致发病率和死亡率增加。年轻女性 TS 面临的健康问题的复杂性或可能出现的新问题，需要制定一个结构良好且协调有效的逐步过渡计划，该计划适应于新兴年轻成人的个体需求，并基于医生之间的跨学科沟通。为了实现高水平的护理，重要的是要让患者真诚地了解自己的病情，并且在这个责任和自主权不断上升的关键时期，还需要有一个经验丰富的多学科团队为其提供支持。在这篇综述中，我们提出了应具有过渡特征的基本概念和应彻底解决的主要健康问题，包括生长、激素替代治疗和生育选择、心血管疾病、骨骼健康、胃肠道疾病、自身免疫、骨科和耳鼻喉科问题以及 TS 年轻成人的整体心理健康。
