Liu Xiaoyan, Yang Jun, Ma Weiyuan
Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China Department of Pulmonary Medicine, Ankang Central Hospital, Ankang Department of Dermatology, Qilu Hospital, Shandong University, Jinan, China.
Medicine (Baltimore). 2017 Dec;96(48):e8916. doi: 10.1097/MD.0000000000008916.
Primary cutaneous aspergillosis in immunocompromised patients has been well described in extensive investigations. However, in immunocompetent hosts, primary cutaneous infection of aspergillus occurs rarely, and remains poorly characterized.
We present a case of primary cutaneous aspergillosis manifested by erythematous plague covered with flava eschar.
The patient was diagnosed with primary cutaneous aspergillosis.
Treatments with oral itraconazole at a dose of 75 mg/d and local wound care with ciclopirox olamine ointment were administered.
After half a month, a partial resolution and a decrease in tenderness indicated gradual improvement, and a complete remission was achieved 2 months later.
Primary cutaneous aspergillosis could occur in immunocompetent hosts. The initial lesions may appear in different forms, including macules, papules, nodules, or plaques. Repeated biopsy of a skin lesion for both culture and histopathology is needed.
免疫功能低下患者的原发性皮肤曲霉病已在广泛研究中得到充分描述。然而，在免疫功能正常的宿主中，曲霉原发性皮肤感染很少发生，且特征仍不明确。
我们报告一例原发性皮肤曲霉病病例，表现为覆盖有黄色焦痂的红斑性脓疱。
该患者被诊断为原发性皮肤曲霉病。
给予口服伊曲康唑，剂量为75毫克/天，并使用环吡酮胺软膏进行局部伤口护理。
半个月后，部分消退和压痛减轻表明病情逐渐改善，2个月后实现完全缓解。
原发性皮肤曲霉病可发生在免疫功能正常的宿主中。初始病变可能以不同形式出现，包括斑疹、丘疹、结节或斑块。需要对皮肤病变进行反复活检以进行培养和组织病理学检查。
