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The nature of the Ca2+-pump defect in the red blood cells of patients with cystic fibrosis.

作者信息

Muallem S, Miner C, Seymour C A

出版信息

Biochim Biophys Acta. 1985 Sep 25;819(1):143-7. doi: 10.1016/0005-2736(85)90205-6.

DOI:10.1016/0005-2736(85)90205-6
PMID:2931115
Abstract

The reduction in (Ca2+ + Mg2+)-ATPase activity in the cystic fibrosis red blood cells can be attributed to a reduction in the number of active Ca2+ pumps per red blood cell and an altered interaction of calcium ions with the pump. Despite this, the normal free intracellular [Ca2+] is preserved due to a lower rate of passive calcium entry.

摘要

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J Physiol. 1997 Dec 1;505 ( Pt 2)(Pt 2):403-10. doi: 10.1111/j.1469-7793.1997.403bb.x.
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J Physiol. 1993 May;464:529-44. doi: 10.1113/jphysiol.1993.sp019649.