Considering hypertonicity in the interpretation and analysis of cell type-specific gene expression pattern in the collecting duct.
作者信息
Edemir Bayram
机构信息
Department of Medicine, Hematology and Oncology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany
出版信息
Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E349-E350. doi: 10.1073/pnas.1720087115. Epub 2018 Jan 8.
Abstract
摘要
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Considering hypertonicity in the interpretation and analysis of cell type-specific gene expression pattern in the collecting duct.在集合管细胞类型特异性基因表达模式的解释和分析中考虑高渗性。
Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E349-E350. doi: 10.1073/pnas.1720087115. Epub 2018 Jan 8.
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引用本文的文献
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Reply to Edemir: Physiological regulation and single-cell RNA sequencing.回复埃代米尔：生理调节与单细胞RNA测序。
Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E351-E352. doi: 10.1073/pnas.1720333115. Epub 2018 Jan 8.
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Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.单细胞 RNA-seq 鉴定的小鼠主要肾集合管细胞类型的转录组。
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2
The kidney-specific expression of genes can be modulated by the extracellular osmolality.基因的肾脏特异性表达可受细胞外渗透压调节。
FASEB J. 2016 Oct;30(10):3588-3597. doi: 10.1096/fj.201600319R. Epub 2016 Jul 27.
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Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes.显微切割肾小管中的深度测序鉴定肾单位节段特异性转录组。
J Am Soc Nephrol. 2015 Nov;26(11):2669-77. doi: 10.1681/ASN.2014111067. Epub 2015 Mar 27.
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Different effects of CsA and FK506 on aquaporin-2 abundance in rat primary cultured collecting duct cells.环孢素 A 和 FK506 对大鼠原代培养集合管细胞水通道蛋白-2 丰度的不同影响。
Pflugers Arch. 2011 Oct;462(4):611-22. doi: 10.1007/s00424-011-0994-6. Epub 2011 Jul 20.
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Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells.心房利钠肽和一氧化氮信号传导拮抗血管加压素介导的髓质内集合管细胞水通透性。
Am J Physiol Renal Physiol. 2009 Sep;297(3):F693-703. doi: 10.1152/ajprenal.00136.2009. Epub 2009 Jul 1.
6
Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells.牛磺酸转运体的表达通过渗透压反应元件（TonE）/渗透压反应元件结合蛋白（TonEBP）途径进行调节，并有助于对HepG2细胞的细胞保护作用。
Biochem J. 2004 Aug 15;382(Pt 1):177-82. doi: 10.1042/BJ20031838.
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Rat renal expression of mRNA coding for aldose reductase and sorbitol dehydrogenase and its osmotic regulation in inner medullary collecting duct cells.大鼠肾脏中醛糖还原酶和山梨醇脱氢酶编码mRNA的表达及其在内髓集合管细胞中的渗透调节。
Cell Physiol Biochem. 1998;8(6):293-303. doi: 10.1159/000016291.
8
Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes.缺乏容量调节机制会导致胸腺细胞中凋亡的快速激活。
Am J Physiol. 1996 Sep;271(3 Pt 1):C950-61. doi: 10.1152/ajpcell.1996.271.3.C950.
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Am J Physiol. 1993 Jan;264(1 Pt 2):F20-3. doi: 10.1152/ajprenal.1993.264.1.F20.
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Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity.一种受高渗调节的 Na⁺ 和 Cl⁻ 依赖性甜菜碱转运体的克隆。
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