Ozaki Kiyokazu, Hirabayashi Masakazu, Nomura Koji, Narama Isao
Laboratory of Pathology, Setsunan University, 45-1 Nagaotohge-cho, Hirakata, Osaka 573-0101, Japan.
All Per Clinic, 2-4-9 Nishi-azabu, Minato-ku, Tokyo 106-0031, Japan.
J Vet Med Sci. 2018 Mar 24;80(3):485-487. doi: 10.1292/jvms.17-0645. Epub 2018 Jan 4.
Lilies are considered nephrotoxic only to domestic cats, which belong to the family Felidae of the suborder Feliformia. However, a 7-month-old female meerkat, belonging to the family Herpestidae of the suborder Feliformia, presented with oliguria, seizure, tachypnea, self-biting, and nystagmus after it ingested lilies. The meerkat died approximately 40 hr after lily ingestion. Gross and histopathologic lesions consistent with acute renal failure were conspicuous in the animal. The renal lesions were acute tubular necrosis, corresponding to the typical pathological changes of lily toxicosis in cats. In addition, massive hepatocyte necrosis and pulmonary congestion/edema were observed. These findings suggest that lily toxicosis in meerkats is characterized by pulmonary and hepatic failure, in addition to the renal failure observed in domestic cats.
百合仅被认为对家猫具有肾毒性，家猫属于猫型亚目猫科动物。然而，一只7个月大的雌性狐獴，属于猫型亚目獴科动物，在摄入百合后出现少尿、癫痫发作、呼吸急促、自咬和眼球震颤。这只狐獴在摄入百合后约40小时死亡。该动物体内出现了与急性肾衰竭相符的大体和组织病理学病变。肾脏病变为急性肾小管坏死，这与猫百合中毒的典型病理变化一致。此外，还观察到大量肝细胞坏死和肺充血/水肿。这些发现表明，狐獴的百合中毒除了具有家猫中观察到的肾衰竭外，还以肺和肝衰竭为特征。
