肝细胞移植：考虑在切开前进行输注。
Hepatocyte transplantation: Consider infusion before incision.
作者信息
Heath Ryan D, Ertem Furkan, Romana Bhupinder S, Ibdah Jamal A, Tahan Veysel
机构信息
Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65212, United States.
Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15260, United States.
出版信息
World J Transplant. 2017 Dec 24;7(6):317-323. doi: 10.5500/wjt.v7.i6.317.
Abstract
Human hepatocyte transplantation is undergoing study as a bridge, or even alternative, to orthotopic liver transplantation (OLT). This technique has undergone multiple developments over the past thirty years in terms of mode of delivery, source and preparation of cell cultures, monitoring of graft function, and use of immunosuppression. Further refinements and improvements in these techniques will likely allow improved graft survival and function, granting patients higher yield from this technique and potentially significantly delaying need for OLT.
摘要
人类肝细胞移植正在作为原位肝移植（OLT）的桥梁甚至替代方法进行研究。在过去三十年中，这项技术在细胞培养物的递送方式、来源和制备、移植物功能监测以及免疫抑制的使用方面经历了多次发展。这些技术的进一步完善和改进可能会提高移植物的存活率和功能，使患者从这项技术中获得更高的收益，并有可能显著推迟对OLT的需求。
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