伴有谱系障碍的一侧半综合征
One-and-a-half syndrome with its spectrum disorders.
作者信息
Xue Fang, Zhang Lihong, Zhang Li, Ying Zhenguang, Sha Ou, Ding Yan
机构信息
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Department of Physiology and Neurology, University of Connecticut, Storrs, USA.
出版信息
Quant Imaging Med Surg. 2017 Dec;7(6):691-697. doi: 10.21037/qims.2017.12.04.
Abstract
One-and-a-half syndrome is a syndrome characterized by horizontal movement disorders of the eyeballs, which was first reported and named by Fisher in 1967. It presents a combination of ipsilateral conjugate horizontal gaze palsy (one) and ipsilateral internuclear ophthalmoplegia (INO) (a half). On the basis of the one-and-a-half syndrome, there are a series of related rare syndromes called the one-and-a-half syndrome spectrum disorders. This article reviews rare cases of one-and-a-half syndrome spectrum disorder, describes the clinical and pathological features of different syndromes, and summarizes their nomenclature.
摘要
一个半综合征是一种以眼球水平运动障碍为特征的综合征，于1967年由费舍尔首次报道并命名。它表现为同侧共轭性水平凝视麻痹（一个）和同侧核间性眼肌麻痹（半个）的组合。在一个半综合征的基础上，有一系列相关的罕见综合征，称为一个半综合征谱系障碍。本文回顾了一个半综合征谱系障碍的罕见病例，描述了不同综合征的临床和病理特征，并总结了它们的命名。
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本文引用的文献
1
Thirteen-And-A-Half Syndrome.十三又二分之一综合征
J Neuroophthalmol. 2016 Jun;36(2):191-2. doi: 10.1097/WNO.0000000000000341.
2
"Nine" syndrome: A new neuro-ophthalmologic syndrome: Report of two cases.“九”综合征：一种新的神经眼科综合征：两例报告
Ann Indian Acad Neurol. 2015 Jul-Sep;18(3):335-7. doi: 10.4103/0972-2327.157180.
3
Diffusion weighted magnetic resonance imaging and its recent trend-a survey.磁共振扩散加权成像及其近期趋势——一项综述
Quant Imaging Med Surg. 2015 Jun;5(3):407-22. doi: 10.3978/j.issn.2223-4292.2015.03.01.
4
Eight and a half syndrome with hemiparesis and hemihypesthesia: the nine syndrome?伴偏瘫和偏身感觉缺失的八又半综合征：九综合征？
J Stroke Cerebrovasc Dis. 2013 Nov;22(8):e637-8. doi: 10.1016/j.jstrokecerebrovasdis.2013.01.018. Epub 2013 Feb 21.
5
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6
"Sixteen and a half": a novel pontine neuro-ophthalmological syndrome.“十六个半”：一种新型脑桥神经眼科综合征
J Neurol. 2011 Jul;258(7):1347-8. doi: 10.1007/s00415-010-5890-z. Epub 2011 Jan 6.
7
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8
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9
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