Xue Fang, Zhang Lihong, Zhang Li, Ying Zhenguang, Sha Ou, Ding Yan
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Department of Physiology and Neurology, University of Connecticut, Storrs, USA.
Quant Imaging Med Surg. 2017 Dec;7(6):691-697. doi: 10.21037/qims.2017.12.04.
One-and-a-half syndrome is a syndrome characterized by horizontal movement disorders of the eyeballs, which was first reported and named by Fisher in 1967. It presents a combination of ipsilateral conjugate horizontal gaze palsy (one) and ipsilateral internuclear ophthalmoplegia (INO) (a half). On the basis of the one-and-a-half syndrome, there are a series of related rare syndromes called the one-and-a-half syndrome spectrum disorders. This article reviews rare cases of one-and-a-half syndrome spectrum disorder, describes the clinical and pathological features of different syndromes, and summarizes their nomenclature.
一个半综合征是一种以眼球水平运动障碍为特征的综合征，于1967年由费舍尔首次报道并命名。它表现为同侧共轭性水平凝视麻痹（一个）和同侧核间性眼肌麻痹（半个）的组合。在一个半综合征的基础上，有一系列相关的罕见综合征，称为一个半综合征谱系障碍。本文回顾了一个半综合征谱系障碍的罕见病例，描述了不同综合征的临床和病理特征，并总结了它们的命名。
