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腹主动脉瘤的流行病学和当代管理。

Epidemiology and contemporary management of abdominal aortic aneurysms.

机构信息

Department of Cardiovascular Surgery, Providence Heart and Vascular Institute, 5050 N.E. Hoyt St., Suite 511, Portland, OR, 97213, USA.

Department of Radiology, Stanford University, Stanford, CA, USA.

出版信息

Abdom Radiol (NY). 2018 May;43(5):1032-1043. doi: 10.1007/s00261-017-1450-7.

Abstract

Abdominal aortic aneurysm (AAA) is most commonly defined as a maximal diameter of the abdominal aorta in excess of 3 cm in either anterior-posterior or transverse planes or, alternatively, as a focal dilation ≥ 1.5 times the diameter of the normal adjacent arterial segment. Risk factors for the development of AAA include age > 60, tobacco use, male gender, Caucasian race, and family history of AAA. Aneurysm growth and rupture risk appear to be associated with persistent tobacco use, female gender, and chronic pulmonary disease. The majority of AAAs are asymptomatic and detected incidentally on various imaging studies, including abdominal ultrasound, and computed tomographic angiography. Symptoms associated with AAA may include abdominal or back pain, thromboembolization, atheroembolization, aortic rupture, or development of an arteriovenous or aortoenteric fistula. The Screening Abdominal Aortic Aneurysms Efficiently (SAAAVE) Act provides coverage for a one-time screening abdominal ultrasound at age 65 for men who have smoked at least 100 cigarettes and women who have family history of AAA disease. Medical management is recommended for asymptomatic patients with AAAs < 5 cm in diameter and focuses on modifiable risk factors, including smoking cessation and blood pressure control. Primary indications for intervention in patients with AAA include development of symptoms, rupture, rapid aneurysm growth (> 5 mm/6 months), or presence of a fusiform aneurysm with maximum diameter of 5.5 cm or greater. Intervention for AAA includes conventional open surgical repair and endovascular aortic stent graft repair.

摘要

腹主动脉瘤(AAA)通常定义为腹主动脉在前后或横切面上的最大直径超过 3 厘米,或者是局部扩张≥正常相邻动脉节段直径的 1.5 倍。AAA 的发展风险因素包括年龄>60 岁、吸烟、男性、白种人以及 AAA 家族史。动脉瘤的生长和破裂风险似乎与持续吸烟、女性和慢性肺部疾病有关。大多数 AAA 是无症状的,在各种影像学研究中偶然发现,包括腹部超声和计算机断层血管造影。与 AAA 相关的症状可能包括腹痛或背痛、血栓栓塞、动脉粥样硬化栓塞、主动脉破裂,或形成动静脉或主动脉肠瘘。高效筛查腹主动脉瘤(SAAAVE)法案为至少吸过 100 支香烟的男性和有 AAA 家族史的女性在 65 岁时提供一次腹部超声筛查。对于直径<5 厘米的无症状 AAA 患者,建议进行医学管理,并侧重于可改变的风险因素,包括戒烟和控制血压。AAA 患者干预的主要指征包括出现症状、破裂、快速动脉瘤生长(>5 毫米/6 个月)、或存在最大直径为 5.5 厘米或更大的梭形动脉瘤。AAA 的干预包括传统的开放手术修复和血管内主动脉支架修复。

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