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Dietary branched chain amino acids and metabolic health: when less is more.膳食支链氨基酸与代谢健康:何时少即是多。
J Physiol. 2018 Feb 15;596(4):555-556. doi: 10.1113/JP275613. Epub 2018 Jan 19.
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Diabetes and branched-chain amino acids: What is the link?糖尿病与支链氨基酸:它们之间有何关联?
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Effect of glucose and/or branched chain amino acid infusion on plasma amino acid imbalance in chronic liver failure.葡萄糖和/或支链氨基酸输注对慢性肝衰竭患者血浆氨基酸失衡的影响。
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Insulin action on glucose and branched-chain amino acid metabolism in cancer cachexia: differential effects of insulin.胰岛素对癌症恶病质中葡萄糖和支链氨基酸代谢的作用:胰岛素的不同效应
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Effects of branched-chain amino acids on placental amino acid transfer and insulin and glucagon release in the ovine fetus.支链氨基酸对绵羊胎儿胎盘氨基酸转运及胰岛素和胰高血糖素释放的影响。
Am J Obstet Gynecol. 2001 Aug;185(2):487-95. doi: 10.1067/mob.2001.116096.

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Dietary Restriction against Parkinson's Disease: What We Know So Far.饮食限制防治帕金森病:现有认识。
Nutrients. 2022 Oct 3;14(19):4108. doi: 10.3390/nu14194108.
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Dietary intake of branched-chain amino acids in relation to general and abdominal obesity.支链氨基酸的饮食摄入与全身和腹部肥胖的关系。
Eat Weight Disord. 2022 May;27(4):1303-1311. doi: 10.1007/s40519-021-01266-6. Epub 2021 Jul 15.
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Daily Branched-Chain Amino Acid Intake and Risks of Obesity and Insulin Resistance in Children: A Cross-Sectional Study.每日支链氨基酸摄入量与儿童肥胖和胰岛素抵抗风险的横断面研究。
Obesity (Silver Spring). 2020 Jul;28(7):1310-1316. doi: 10.1002/oby.22834. Epub 2020 Jun 8.
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Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation.精细单倍型图谱分析 MUT、AACS、SLC6A15 和 PRKCA 基因与代谢综合征胰岛素抵抗的关联,以及与支链氨基酸代谢或调控的关系。
PLoS One. 2019 Mar 26;14(3):e0214122. doi: 10.1371/journal.pone.0214122. eCollection 2019.
5
Metabolic profile analysis of free amino acids in experimental autoimmune uveoretinitis rat plasma.实验性自身免疫性葡萄膜视网膜炎大鼠血浆中游离氨基酸的代谢谱分析
Int J Ophthalmol. 2019 Jan 18;12(1):16-24. doi: 10.18240/ijo.2019.01.03. eCollection 2019.
6
Development of Biomarkers for Inhibition of SLC6A19 (B⁰AT1)-A Potential Target to Treat Metabolic Disorders.开发抑制 SLC6A19(B⁰AT1)的生物标志物——治疗代谢紊乱的潜在靶点。
Int J Mol Sci. 2018 Nov 14;19(11):3597. doi: 10.3390/ijms19113597.

本文引用的文献

1
Restoration of metabolic health by decreased consumption of branched-chain amino acids.通过减少支链氨基酸的摄入来恢复代谢健康。
J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27.
2
Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.支链氨基酸补充可逆转 mTORC1 信号,但不能改善饮食蛋白稀释时的代谢。
Mol Metab. 2017 Jun 24;6(8):873-881. doi: 10.1016/j.molmet.2017.06.009. eCollection 2017 Aug.
3
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.减少支链氨基酸的摄入量可改善代谢健康。
Cell Rep. 2016 Jul 12;16(2):520-530. doi: 10.1016/j.celrep.2016.05.092. Epub 2016 Jun 23.
4
FGF21 is an endocrine signal of protein restriction.成纤维细胞生长因子21是蛋白质限制的一种内分泌信号。
J Clin Invest. 2014 Sep;124(9):3913-22. doi: 10.1172/JCI74915. Epub 2014 Aug 18.
5
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.一种与支链氨基酸相关的代谢特征,可区分肥胖和消瘦人群,并导致胰岛素抵抗。
Cell Metab. 2009 Apr;9(4):311-26. doi: 10.1016/j.cmet.2009.02.002.
6
Splanchnic glucose and amino acid metabolism in obesity.肥胖状态下的内脏葡萄糖和氨基酸代谢
J Clin Invest. 1974 Feb;53(2):582-90. doi: 10.1172/JCI107593.

Dietary branched chain amino acids and metabolic health: when less is more.

作者信息

Hill Cristal M, Morrison Christopher D

机构信息

Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.

出版信息

J Physiol. 2018 Feb 15;596(4):555-556. doi: 10.1113/JP275613. Epub 2018 Jan 19.

DOI:10.1113/JP275613
PMID:29313984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5813618/
Abstract
摘要