Vandecasteele T, Van Den Broeck W, Tay H, Couck L, van Loon G, Cornillie P
Department of Morphology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Anat Histol Embryol. 2018 Apr;47(2):145-152. doi: 10.1111/ahe.12334. Epub 2018 Jan 3.
The myocardial sleeve of the porcine and equine pulmonary veins were histologically investigated and reconstructed three dimensionally. Moreover, the localization of neuron cell bodies at the veno-atrial junction and alongside the myocardial sleeve was light microscopically visualized to depict the organization of nerve, myocardial and fat tissue. Finally, the presence of telocytes inside the equine pulmonary veins was demonstrated by use of transmission electron microscopy. These structures are thought to play a role in the induction of atrial fibrillation, which is frequently seen in horses, while pigs are often used as a cardiovascular model in this context. This data fills in remaining gaps in the literature concerning the histological build-up of the pulmonary veins wall in pigs and horses. In-depth knowledge on the myocardial sleeve and its surrounding cell types are important to understand the possible outcome of an ablation therapy as an atrial fibrillation treatment. In pigs and horses, the layout of the pulmonary veins wall concerning these structures is comparable to humans. However, neuron cell bodies were recovered at the veno-atrial junction in both species but not alongside the myocardial sleeve in horses.
对猪和马的肺静脉心肌袖进行了组织学研究并进行三维重建。此外，通过光学显微镜观察静脉-心房交界处及心肌袖旁神经细胞体的定位，以描绘神经、心肌和脂肪组织的组织结构。最后，利用透射电子显微镜证实马肺静脉内存在间质细胞。这些结构被认为在马中常见的心房颤动的诱发中起作用，而在此背景下猪常被用作心血管模型。该数据填补了关于猪和马肺静脉壁组织学构成的文献中剩余的空白。深入了解心肌袖及其周围细胞类型对于理解作为心房颤动治疗方法的消融治疗的可能结果很重要。在猪和马中，这些结构的肺静脉壁布局与人类相似。然而，在这两个物种的静脉-心房交界处均发现了神经细胞体，但在马的心肌袖旁未发现。
