CU Sports Medicine, Department of Orthopedics, University of Colorado School of Medicine, Boulder, Colorado, USA.
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Am J Sports Med. 2018 Mar;46(3):573-580. doi: 10.1177/0363546517744202. Epub 2018 Jan 9.
Osteochondral allograft transplantation (OCA) is often performed with concomitant meniscus allograft transplantation (MAT) as a strategy for knee joint preservation, although to date, the effect of concomitant MAT on outcomes and failure rates after OCA has not been assessed.
To determine clinical outcomes for patients undergoing OCA with MAT as compared with a matched cohort of patients undergoing isolated OCA.
Control study; Level of evidence, 3.
Patients who underwent OCA of the medial or lateral femoral condyle without concomitant MAT by a single surgeon were compared with a matched group of patients who underwent OCA with concomitant MAT (ipsilateral compartment). The patients were matched per age, sex, body mass index, and number of previous ipsilateral knee operations ±1. Patient-reported outcomes, complications, reoperations, and survival rates were compared between groups.
One hundred patients undergoing OCA (50 isolated, 50 with MAT) with a mean ± SD follow-up of 4.9 ± 2.7 years (minimum, 2 years) were included (age, 31.7 ± 9.8 years; 52% male). Significantly more patients underwent OCA to the medial femoral condyle (n = 59) than the lateral femoral condyle (n = 41, P < .0001). Patients underwent 2.7 ± 1.7 operations on the ipsilateral knee before OCA. There were no significant differences between the groups regarding reoperation rate (n = 18 for OCA with MAT, n = 17 for OCA without MAT, P = .834), time to reoperation (2.2 ± 2.4 years for OCA with MAT, 3.4 ± 2.7 years for OCA without MAT, P = .149), or failure rates (n = 7 [14%] for OCA with MAT, n = 7 [14%] for OCA without MAT, P > .999). There were no significant differences in patient-reported clinical outcome scores between the groups at final follow-up. There was no significant difference in failure rates between patients undergoing medial femoral condyle OCA (n = 12, 15.3%) and lateral femoral condyle OCA (n = 5, 12.2%, P = .665).
These results imply that with appropriate surgical indications to address meniscus deficiency in patients otherwise indicated for OCA and despite the added surgical time and complexity of concomitant MAT, outcomes are favorable, with an 86% OCA graft survivorship at 5 years. This information can be used to counsel patients undergoing OCA with concomitant MAT as part of a knee joint preservation strategy.
骨软骨同种异体移植(OCA)常与半月板同种异体移植(MAT)同时进行,作为膝关节保存的一种策略,尽管迄今为止,OCA 后同时进行 MAT 对结果和失败率的影响尚未得到评估。
确定同时进行 MAT 的 OCA 患者与单独进行 OCA 的匹配队列患者的临床结果。
对照研究;证据水平,3 级。
对一名外科医生行内侧或外侧股骨髁 OCA 且无同时进行 MAT 的患者与同时进行 MAT(同侧关节)的匹配组患者进行比较。患者按年龄、性别、体重指数和同侧膝关节手术次数±1 进行匹配。比较两组患者的报告结果、并发症、再次手术和生存率。
共纳入 100 例接受 OCA(50 例单独接受 OCA,50 例同时接受 MAT)的患者,平均随访 4.9±2.7 年(最短 2 年)(年龄 31.7±9.8 岁;52%为男性)。接受内侧股骨髁 OCA 的患者明显多于外侧股骨髁 OCA(n=59 比 n=41,P<.0001)。在 OCA 前,患者同侧膝关节接受了 2.7±1.7 次手术。两组之间的再手术率(MAT 组 n=18,无 MAT 组 n=17,P=.834)、再手术时间(MAT 组 2.2±2.4 年,无 MAT 组 3.4±2.7 年,P=.149)或失败率(MAT 组 n=7[14%],无 MAT 组 n=7[14%],P>.999)均无显著差异。最终随访时,两组患者的报告临床结局评分无显著差异。内侧股骨髁 OCA 组(n=12,15.3%)和外侧股骨髁 OCA 组(n=5,12.2%,P=.665)的失败率无显著差异。
这些结果表明,对于有适当手术适应证的患者,为了治疗半月板缺失,同时进行 OCA 和 MAT 尽管增加了手术时间和复杂性,但结果是有利的,5 年时 OCA 移植物存活率为 86%。这些信息可用于 OCA 同时进行 MAT 的患者提供咨询,作为膝关节保存策略的一部分。