Wang Xiaogang, Zhang Zhe, Li Xiaoyan, Xie Lisha, Zhang Haining, Koch Douglas D, Wang Li, Zhang Suhua
J Refract Surg. 2018 Jan 1;34(1):17-22. doi: 10.3928/1081597X-20171109-01.
To investigate the wound healing changes of clear corneal incisions performed with a femtosecond laser or a steel bevel knife in cataract surgery using spectral-domain optical coherence tomography.
Prospectively, consecutive patients undergoing either femtosecond laser-assisted cataract surgery (femtosecond laser group) using the LenSx laser (Alcon Laboratories, Inc., Fort Worth, TX) or traditional cataract surgery using steel blades (control group) were enrolled. The incidence of posterior wound gape, Descemet's membrane detachment, posterior wound retraction, and the inner and outer corneal incision thicknesses were assessed.
Compared to the control group, the femtosecond laser group had significantly lower incidences of posterior wound gape at 1 day (P = .012) and Descemet's membrane detachment at 1 week (P = .030), 1 month (P = .048), and 3 months (P = .048), and a significantly higher incidence of posterior wound retraction at 1 month (P < .001) and 3 months (P < .001) postoperatively. The inner and outer corneal incision thicknesses decreased over time in both groups.
The clear corneal incisions created by femtosecond laser demonstrated a lower incidence of posterior wound gape and Descemet's membrane detachment. However, the higher posterior wound retraction incidence, which indicated that there was wound remodeling, was apparent. [J Refract Surg. 2018;34(1):17-22.].
使用频域光学相干断层扫描技术研究在白内障手术中，飞秒激光或钢斜角刀制作的透明角膜切口的伤口愈合变化。
前瞻性地纳入连续接受使用LenSx激光（爱尔康实验室公司，沃思堡，德克萨斯州）的飞秒激光辅助白内障手术（飞秒激光组）或使用钢刀片的传统白内障手术（对照组）的患者。评估后伤口裂开、Descemet膜脱离、后伤口回缩的发生率以及角膜内外切口厚度。
与对照组相比，飞秒激光组术后1天的后伤口裂开发生率显著更低（P = .012），术后1周（P = .030）、1个月（P = .048）和3个月（P = .048）的Descemet膜脱离发生率显著更低，术后1个月（P < .001）和3个月（P < .001）的后伤口回缩发生率显著更高。两组角膜内外切口厚度均随时间下降。
飞秒激光制作的透明角膜切口后伤口裂开和Descemet膜脱离的发生率较低。然而，后伤口回缩发生率较高，这表明存在伤口重塑现象，这一点很明显。[《屈光手术杂志》。2018年；34(1):17 - 22。]
