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飞秒激光辅助白内障手术后的干眼:见解与预防策略

Postoperative dry eye following femtosecond laser-assisted cataract surgery: insights and preventive strategies.

作者信息

Lin Bin, Li Dong-Kan, Zhang Ling, Chen Long-Long, Gao Ying-Ying

机构信息

School of Medicine, Xiamen Eye Center and Eye Institute of Xiamen University, Xiamen, China.

Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China.

出版信息

Front Med (Lausanne). 2024 Nov 18;11:1443769. doi: 10.3389/fmed.2024.1443769. eCollection 2024.

DOI:10.3389/fmed.2024.1443769
PMID:39624035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11608956/
Abstract

Postoperative dry eye is a common complication following femtosecond laser-assisted cataract surgery, and the patient interface (PI) used during the procedure may play a significant role in its occurrence. This study, utilizing a meticulous scientific search strategy, identified seven relevant articles through literature search engines. Most of these studies employed contact-type PI during surgeries, while one researcher used a non-contact PI. All studies assessed dry eye symptoms at various postoperative periods using metrics such as the Ocular Surface Disease Index (OSDI), tear Break-Up Time (BUT), Schirmer I test (SIt), and so on. However, the findings were inconsistent. On this basis, this comprehensive review delves into the potential impact of different patient interfaces on corneal nerve damage and conjunctival goblet cell injury, possibly contributing to an increased risk of postoperative dry eye. The review also explores various preventive and solution strategies, including improving PI design, reducing surgical time, and utilizing tear protective agents. The findings highlight the importance of optimizing the PI to minimize the risk of postoperative dry eye in femtosecond laser-assisted cataract surgery.

摘要

术后干眼是飞秒激光辅助白内障手术后常见的并发症,手术过程中使用的患者界面(PI)可能在其发生中起重要作用。本研究采用严谨的科学检索策略,通过文献搜索引擎确定了7篇相关文章。这些研究大多在手术中使用接触式PI,而有一位研究者使用了非接触式PI。所有研究均使用眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪液分泌试验I(SIt)等指标在术后不同时期评估干眼症状。然而,研究结果并不一致。在此基础上,本综述深入探讨了不同患者界面对角膜神经损伤和结膜杯状细胞损伤的潜在影响,这可能会增加术后干眼的风险。该综述还探讨了各种预防和解决策略,包括改进PI设计、缩短手术时间和使用泪液保护剂。研究结果强调了优化PI以降低飞秒激光辅助白内障手术中术后干眼风险的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af15/11608956/ff64518a18a3/fmed-11-1443769-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af15/11608956/595d013215f7/fmed-11-1443769-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af15/11608956/ff64518a18a3/fmed-11-1443769-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af15/11608956/595d013215f7/fmed-11-1443769-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af15/11608956/ff64518a18a3/fmed-11-1443769-g002.jpg

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本文引用的文献

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Cochrane Database Syst Rev. 2023 Jun 23;6(6):CD010735. doi: 10.1002/14651858.CD010735.pub3.
2
Accuracy of the LaserArcs Femtosecond Cataract Surgery Arcuate Incision Nomogram in Patients Undergoing Cataract Surgery and Astigmatism Reduction.激光弧飞秒白内障手术弧形切口列线图在白内障手术及散光矫正患者中的准确性
Clin Ophthalmol. 2023 Feb 27;17:681-689. doi: 10.2147/OPTH.S398334. eCollection 2023.
3
Dry Eye Following Femtosecond Laser-Assisted Cataract Surgery: A Meta-Analysis.
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J Clin Med. 2022 Oct 22;11(21):6228. doi: 10.3390/jcm11216228.
4
Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis.白内障手术后干眼疾病的患病率及特征:一项系统评价和Meta分析
Ophthalmol Ther. 2022 Aug;11(4):1309-1332. doi: 10.1007/s40123-022-00513-y. Epub 2022 May 9.
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Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine.干眼症的发病机制与治疗新进展:抗炎和免疫调节治疗与传统中医
Front Med (Lausanne). 2022 Jan 17;8:815075. doi: 10.3389/fmed.2021.815075. eCollection 2021.
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Femtosecond Laser Assisted Cataract Surgery: A Review.飞秒激光辅助白内障手术:综述。
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