Department of Dermatology, College of Medicine, The Catholic University of Korea, Uijeongbu St Mary's Hospital, Gyeonggi-do, Korea.
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, Korea.
J Dermatol. 2018 Apr;45(4):463-467. doi: 10.1111/1346-8138.14193. Epub 2018 Jan 4.
This study investigated the association between allergic diseases and comorbid ophthalmologic diseases. We enrolled 14 776 participants who were at least 19 years of age. Multiple logistic regression analyses were used to evaluate the odds ratios for cataracts and glaucoma according to the presence of allergic diseases. Atopic dermatitis was not associated with the development of cataracts and glaucoma. However, asthma and allergic rhinitis were significantly associated with cataracts (hazard ratio [HR] = 1.511, 95% confidence interval [CI] = 1.120-2.039 and HR = 1.565, 95% CI = 1.192-2.054, respectively). This study examined a nationwide, population-based survey, and concluded that cataracts were significantly associated with asthma and allergic rhinitis but not with atopic dermatitis. Efforts should be made to reduce the risk of ophthalmologic complications when treating patients with allergic diseases.
本研究调查了过敏性疾病与合并眼科疾病之间的关联。我们纳入了至少 19 岁的 14776 名参与者。采用多因素 logistic 回归分析评估了存在过敏性疾病时白内障和青光眼的比值比。特应性皮炎与白内障和青光眼的发生无关。然而,哮喘和过敏性鼻炎与白内障显著相关(危险比[HR] = 1.511,95%置信区间[CI] = 1.120-2.039 和 HR = 1.565,95%CI = 1.192-2.054)。本研究对一项全国性、基于人群的调查进行了分析,得出结论认为白内障与哮喘和过敏性鼻炎显著相关,但与特应性皮炎无关。在治疗过敏性疾病患者时,应努力降低眼科并发症的风险。