肠道菌群与肝脏。
Microbiota and the liver.
机构信息
Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Department of Gastroenterology and Hepatology, Rutgers New Jersey Medical School, Newark, NJ.
出版信息
Liver Transpl. 2018 Apr;24(4):539-550. doi: 10.1002/lt.25008.
The gut microbiome outnumbers the human genome by 150-fold and plays important roles in metabolism, immune system education, tolerance development, and prevention of pathogen colonization. Dysbiosis has been associated with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and alcoholic liver disease (ALD) as well as cirrhosis and complications. This article provides an overview of this relationship. Liver Transplantation 24 539-550 2018 AASLD.
肠道微生物组的数量是人类基因组的 150 倍，在新陈代谢、免疫系统教育、耐受发展和预防病原体定植方面发挥着重要作用。肠道菌群失调与非酒精性脂肪性肝病（NAFLD）、非酒精性脂肪性肝炎（NASH）和酒精性肝病（ALD）以及肝硬化和并发症有关。本文就这种关系进行了综述。《肝脏移植》24 卷 539-550 页 2018 年美国肝病研究学会。
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