Novel 4-Methylumbelliferone Amide Derivatives: Synthesis, Characterization and Pesticidal Activities.

A series of novel 4-methylumbelliferone amide derivatives were designed, synthesized and characterized by ¹H NMR, C NMR and HR-ESI-MS. The structures of compounds and (compounds named by authors) were further confirmed by X-ray single crystal diffraction. The acaricidal, herbicidal and antifungal activities of the synthesized compounds were assayed for their potential use as pesticide. The results indicated that compounds , and were strong acaricidals against , with 72h corrected mortalities of greater than 80% at 1000 mg/L. Meanwhile, compounds and exhibit the strongest inhibition against the taproot development of and , and were even more potent than the commercial herbicide Acetochlor against . In addition, compounds , and showed the highest antifungal activity against the mycelium growth of , which makes them more effective than commercial fungicide Carbendazim.