McLaughlin James Alastair, Myers Chris J, Zundel Zach, Mısırlı Göksel, Zhang Michael, Ofiteru Irina Dana, Goñi-Moreno Angel, Wipat Anil
School of Computing, Newcastle University , Newcastle upon Tyne, NE1 7RU, U.K.
Department of Electrical and Computer Engineering, University of Utah , Salt Lake City, Utah 84112, United States.
ACS Synth Biol. 2018 Feb 16;7(2):682-688. doi: 10.1021/acssynbio.7b00403. Epub 2018 Jan 30.
The SynBioHub repository ( https://synbiohub.org ) is an open-source software project that facilitates the sharing of information about engineered biological systems. SynBioHub provides computational access for software and data integration, and a graphical user interface that enables users to search for and share designs in a Web browser. By connecting to relevant repositories (e.g., the iGEM repository, JBEI ICE, and other instances of SynBioHub), the software allows users to browse, upload, and download data in various standard formats, regardless of their location or representation. SynBioHub also provides a central reference point for other resources to link to, delivering design information in a standardized format using the Synthetic Biology Open Language (SBOL). The adoption and use of SynBioHub, a community-driven effort, has the potential to overcome the reproducibility challenge across laboratories by helping to address the current lack of information about published designs.
合成生物学中心库(https://synbiohub.org)是一个开源软件项目,有助于共享有关工程生物系统的信息。合成生物学中心库提供用于软件和数据集成的计算访问,以及一个图形用户界面,使用户能够在网络浏览器中搜索和共享设计。通过连接到相关存储库(例如国际遗传工程机器大赛(iGEM)存储库、联合生物能源研究所集成合成环境(JBEI ICE)以及合成生物学中心库的其他实例),该软件允许用户浏览、上传和下载各种标准格式的数据,无论其位置或表示形式如何。合成生物学中心库还为其他资源提供了一个中央参考点以供链接,并使用合成生物学开放语言(SBOL)以标准化格式提供设计信息。合成生物学中心库是一项由社区推动的工作,其采用和使用有可能通过帮助解决当前已发表设计信息不足的问题,克服各实验室之间的可重复性挑战。