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草药医学用于治疗癫痫患者:秘鲁北部农村社区的一项调查。

Herbal medicine uses to treat people with epilepsy: A survey in rural communities of northern Peru.

机构信息

INSERM, U1094, Tropical Neuroepidemiology, 2 rue du Dr Marcland, 87025 Limoges, France; Univ. Limoges, UMR 1094, Tropical Neuroepidemiology, Institute of Neuroepidemiology and Tropical Neurology, 2 rue du Dr Marcland, 87025 Limoges, France.

INSERM, U1094, Tropical Neuroepidemiology, 2 rue du Dr Marcland, 87025 Limoges, France; Univ. Limoges, UMR 1094, Tropical Neuroepidemiology, Institute of Neuroepidemiology and Tropical Neurology, 2 rue du Dr Marcland, 87025 Limoges, France; Cysticercosis Elimination Program and Center for Global Health Tumbes, University Peruana Cayetano Heredia, Avenida Panamericana Norte, Tumbes, Peru.

出版信息

J Ethnopharmacol. 2018 Apr 6;215:184-190. doi: 10.1016/j.jep.2018.01.003. Epub 2018 Jan 6.

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Epilepsy affects 150,000 people in Peru, with a prevalence of 16.6/1000 and a treatment gap of 75%. Herbal medicine (HM) is widely used in this country.

AIM OF THE STUDY

We aimed to assess the use of plants in a rural community in northern Peru as part of therapeutic strategies for people with epilepsy (PWE).

MATERIALS AND METHODS

The study was a cross-sectional observational and descriptive study. The inclusion criteria for people with epilepsy were 2 years of age and over, having lived in the study area for at least 3 months and a confirmed diagnosis of epilepsy by a neurologist. The information was gathered through structured interviews using a survey questionnaire. Botanical species used by people with epilepsy or traditional healers were collected and identified.

RESULTS

Out of the 228 people with epilepsy included, 60.0% had used herbal remedies and 54.8% both herbal medicine and anti-epileptic drugs. The traditional healer was the first practitioner consulted by 45.2% of people with epilepsy. Sixty-six species have been mentioned by the people with epilepsy and traditional healers on the treatment of epilepsy. Carbamazepine was the most prescribed anti-epileptic drug with 33.2% of prescriptions.

CONCLUSIONS

This study was the first to measure a percentage of use of herbal medicine for epilepsy in Peru. It would be interesting to conduct a pharmacological evaluation of the most commonly used species on epileptic models to validate and secure their use.

摘要

民族药理学相关性

在秘鲁,有 15 万人患有癫痫,患病率为 16.6/1000,治疗缺口为 75%。草药(HM)在该国被广泛使用。

研究目的

我们旨在评估秘鲁北部一个农村社区中植物的使用情况,作为治疗癫痫患者(PWE)的治疗策略的一部分。

材料和方法

该研究是一项横断面观察性和描述性研究。癫痫患者的纳入标准为年龄在 2 岁及以上,在研究区域居住至少 3 个月,并且经过神经病学家确诊为癫痫。通过使用问卷调查的结构化访谈收集信息。收集了癫痫患者或传统治疗师使用的植物物种信息,并对其进行了鉴定。

结果

在纳入的 228 名癫痫患者中,有 60.0%使用了草药疗法,有 54.8%同时使用了草药和抗癫痫药物。传统治疗师是 45.2%癫痫患者首先咨询的医生。有 66 种物种被癫痫患者和传统治疗师提到用于治疗癫痫。卡马西平是最常开的抗癫痫药物,处方占 33.2%。

结论

这项研究首次测量了秘鲁使用草药治疗癫痫的比例。对最常用于癫痫模型的常用物种进行药理学评估,以验证和确保其使用,这将是很有趣的。

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