DiBonaventura Marco D, Meincke Henrik, Le Lay Agathe, Fournier Janine, Bakker Erik, Ehrenreich Allison
Kantar Health, New York, NY, USA.
Novo Nordisk, Copenhagen, Denmark.
Diabetes Metab Syndr Obes. 2017 Dec 22;11:1-10. doi: 10.2147/DMSO.S129247. eCollection 2018.
The goal of this study is to investigate obesity and its concomitant effects including the prevalence of comorbidities, its association with patient-reported outcomes and costs, and weight loss strategies in a sample of Mexican adults.
Mexican adults (N=2,511) were recruited from a combination of Internet panels and street intercepts using a random-stratified sampling framework, with strata defined by age and sex, so that they represent the population. Participants responded to a survey consisting of a range of topics including sociodemographics, health history, health-related quality of life (HRQoL), work productivity, health care resource use, and weight loss.
The sample consisted of 50.6% male with a mean age of 40.7 years (SD=14.5); 38.3% were overweight, and 24.4% were obese. Increasing body mass index (BMI) was associated with increased rates of type 2 diabetes, prediabetes, and hypertension, poorer HRQoL, and decreased work productivity. Of the total number of respondents, 62.2% reported taking steps to lose weight with 27.6% and 17.1% having used an over-the-counter/herbal product and a prescription medication, respectively. Treatment discontinuation rates were high.
Findings indicated that 62% of participants reported, at least, being overweight and that they were experiencing the deleterious effects associated with higher BMI despite the desire to lose weight. Given the rates of obesity, and its impact on humanistic and societal outcomes, improved education, prevention, and management could provide significant benefits.
本研究的目的是调查墨西哥成年人群样本中的肥胖情况及其伴随影响,包括合并症的患病率、其与患者报告结局及成本的关联,以及减肥策略。
采用随机分层抽样框架,从互联网面板和街头拦截相结合的方式招募墨西哥成年人(N = 2511),按年龄和性别分层,以使其代表总体人群。参与者回答了一项涵盖一系列主题的调查问卷,包括社会人口统计学、健康史、健康相关生活质量(HRQoL)、工作生产力、医疗资源使用情况以及减肥情况。
样本中男性占50.6%,平均年龄为40.7岁(标准差 = 14.5);38.3%超重,24.4%肥胖。体重指数(BMI)增加与2型糖尿病、糖尿病前期和高血压的发病率增加、HRQoL较差以及工作生产力下降相关。在所有受访者中,62.2%报告采取了减肥措施,其中分别有27.6%和17.1%使用了非处方/草药产品和处方药。治疗中断率很高。
研究结果表明,62%的参与者报告至少超重,并且尽管他们有减肥意愿,但仍在经历与较高BMI相关的有害影响。鉴于肥胖率及其对人文和社会结局的影响,改善教育、预防和管理可能会带来显著益处。