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Rockall评分大于7作为非静脉曲张性上消化道出血初次内镜止血后高危老年患者亚组预防性经动脉栓塞术适应证选择的可靠标准。

Rockall Score Larger Than 7 as a Reliable Criterion for the Selection of Indications for Preventive Transarterial Embolization in a Subgroup of High-Risk Elderly Patients After Primary Endoscopic Hemostasis for Non-Variceal Upper Gastrointestinal Bleeding.

作者信息

Kaminskis Aleksejs, Ivanova Patricija, Ponomarjova Sanita, Mukans Maksims, Boka Viesturs, Pupelis Guntars

机构信息

Department of General and Emergency Surgery, Riga East University Hospital, Riga, Latvia.

Department of Interventional Radiology, Riga East University Hospital, Riga, Latvia.

出版信息

Gastroenterology Res. 2017 Dec;10(6):339-346. doi: 10.14740/gr909w. Epub 2018 Jan 3.

DOI:10.14740/gr909w
PMID:29317941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5755635/
Abstract

BACKGROUND

Transarterial embolization (TAE) is an alternative procedure to repeat endoscopy or surgical intervention in the case of re-bleeding after primary endoscopic treatment. The aim of the study was to assess the Rockall score as a criterion for TAE in the case of re-bleeding after endoscopic treatment of non-variceal upper gastrointestinal bleeding (NVUGIB).

METHODS

Out of the 673 patients who underwent emergent endoscopic hemostasis due to NVUGIB, 111 had a high risk of re-bleeding having a Forrest I-IIb ulcer and the Rockall score ≥ 5. From 111 patients, 37 accepted preventive TAE (PE+ group). The control group consisted of 74 patients who underwent standard treatment (PE- group).

RESULTS

There were no differences in the demographic status between both groups, nor in the main clinical data on admission. The performance of TAE resulted in a significantly lower re-bleeding rate (1 (4.8%) vs. 11 (33%), P = 0.018). No patient who underwent TAE with the Rockall score ≥ 7 required surgery, resulting in only one re-bleeding episode (P = 0.004). Mortality reached 5% and 11% in the PE+ and PE- groups accordingly.

CONCLUSION

The Rockall score ≥ 7 could be a reliable predictor of re-bleeding after primary endoscopic hemostasis as one criterion for the selection of indications for preventive TAE.

摘要

背景

经动脉栓塞术(TAE)是在初次内镜治疗后再出血时替代重复内镜检查或手术干预的一种方法。本研究的目的是评估Rockall评分作为非静脉曲张性上消化道出血(NVUGIB)内镜治疗后再出血时TAE的标准。

方法

在因NVUGIB接受急诊内镜止血的673例患者中,111例因存在Forrest I-IIb级溃疡且Rockall评分≥5而有再出血的高风险。在这111例患者中,37例接受了预防性TAE(PE+组)。对照组由74例接受标准治疗的患者组成(PE-组)。

结果

两组患者的人口统计学状况以及入院时的主要临床数据均无差异。TAE的实施使再出血率显著降低(1例(4.8%)对11例(33%),P = 0.018)。Rockall评分≥7接受TAE的患者均无需手术,仅发生1次再出血事件(P = 0.004)。PE+组和PE-组的死亡率分别为5%和11%。

结论

Rockall评分≥7可作为初次内镜止血后再出血的可靠预测指标,作为预防性TAE适应证选择的标准之一。

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本文引用的文献

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Bleeding gastric and duodenal ulcers: case-control study comparing angioembolization and surgery.胃和十二指肠溃疡出血:比较血管栓塞术与手术治疗的病例对照研究
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Preventive transarterial embolization in upper nonvariceal gastrointestinal bleeding.预防性经动脉栓塞在上消化道非静脉曲张性出血中的应用。
World J Emerg Surg. 2017 Jan 13;12:3. doi: 10.1186/s13017-016-0114-1. eCollection 2017.
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Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study.上消化道出血患者风险评分系统的比较:国际多中心前瞻性研究
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Comparison of Glasgow-Blatchford score and full Rockall score systems to predict clinical outcomes in patients with upper gastrointestinal bleeding.比较格拉斯哥-布拉奇福德评分系统和完整的罗卡尔评分系统对预测上消化道出血患者临床结局的作用。
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