Kaminskis Aleksejs, Ivanova Patricija, Ponomarjova Sanita, Mukans Maksims, Boka Viesturs, Pupelis Guntars
Department of General and Emergency Surgery, Riga East University Hospital, Riga, Latvia.
Department of Interventional Radiology, Riga East University Hospital, Riga, Latvia.
Gastroenterology Res. 2017 Dec;10(6):339-346. doi: 10.14740/gr909w. Epub 2018 Jan 3.
Transarterial embolization (TAE) is an alternative procedure to repeat endoscopy or surgical intervention in the case of re-bleeding after primary endoscopic treatment. The aim of the study was to assess the Rockall score as a criterion for TAE in the case of re-bleeding after endoscopic treatment of non-variceal upper gastrointestinal bleeding (NVUGIB).
Out of the 673 patients who underwent emergent endoscopic hemostasis due to NVUGIB, 111 had a high risk of re-bleeding having a Forrest I-IIb ulcer and the Rockall score ≥ 5. From 111 patients, 37 accepted preventive TAE (PE+ group). The control group consisted of 74 patients who underwent standard treatment (PE- group).
There were no differences in the demographic status between both groups, nor in the main clinical data on admission. The performance of TAE resulted in a significantly lower re-bleeding rate (1 (4.8%) vs. 11 (33%), P = 0.018). No patient who underwent TAE with the Rockall score ≥ 7 required surgery, resulting in only one re-bleeding episode (P = 0.004). Mortality reached 5% and 11% in the PE+ and PE- groups accordingly.
The Rockall score ≥ 7 could be a reliable predictor of re-bleeding after primary endoscopic hemostasis as one criterion for the selection of indications for preventive TAE.
经动脉栓塞术(TAE)是在初次内镜治疗后再出血时替代重复内镜检查或手术干预的一种方法。本研究的目的是评估Rockall评分作为非静脉曲张性上消化道出血(NVUGIB)内镜治疗后再出血时TAE的标准。
在因NVUGIB接受急诊内镜止血的673例患者中,111例因存在Forrest I-IIb级溃疡且Rockall评分≥5而有再出血的高风险。在这111例患者中,37例接受了预防性TAE(PE+组)。对照组由74例接受标准治疗的患者组成(PE-组)。
两组患者的人口统计学状况以及入院时的主要临床数据均无差异。TAE的实施使再出血率显著降低(1例(4.8%)对11例(33%),P = 0.018)。Rockall评分≥7接受TAE的患者均无需手术,仅发生1次再出血事件(P = 0.004)。PE+组和PE-组的死亡率分别为5%和11%。
Rockall评分≥7可作为初次内镜止血后再出血的可靠预测指标,作为预防性TAE适应证选择的标准之一。