Wambura Casmir, Surani Salim
Aga Khan University, Dar es Salaam, Tanzania.
Texas A&M University, College Station, TX, USA.
Case Rep Gastrointest Med. 2017;2017:4014565. doi: 10.1155/2017/4014565. Epub 2017 Nov 26.
Plexiform fibromyxoma is a rare and distinctive benign mesenchymal neoplasm that occurs in the gastric antrum. This tumor has a potential for misdiagnosis as gastrointestinal stromal tumor (GIST). It causes mucosa and vascular ulcerations without advancement of the tumor. Cytological bland spindle cells within a variably myxoid stroma characterize the histology of the tumor. We report the case of a 41-year-old African Tanzanian lady who presented with melena and recurrent anemia. Endoscopy and imaging studies revealed antral mass with initial suspicion of a GIST. However, immunohistochemically it turned to be a plexiform fibromyxoma. Follow-up evaluation 12 months after surgery revealed no evidence of recurrence or metastasis. This is a very uncommon tumor, which, to our knowledge, has been reported only once in Africa. The clinicians need to be aware of this rare occurrence to avoid misdiagnosis as GIST tumor.
丛状纤维黏液瘤是一种罕见且独特的良性间叶性肿瘤，发生于胃窦部。该肿瘤有可能被误诊为胃肠道间质瘤（GIST）。它会导致黏膜和血管溃疡，但肿瘤并无进展。肿瘤组织学特征为在不同程度的黏液样基质内有细胞形态温和的梭形细胞。我们报告一例41岁的非洲坦桑尼亚女性病例，该患者表现为黑便和反复贫血。内镜检查和影像学研究显示胃窦部肿块，最初怀疑为GIST。然而，免疫组化结果显示为丛状纤维黏液瘤。术后12个月的随访评估未发现复发或转移迹象。这是一种非常罕见的肿瘤，据我们所知，在非洲仅报道过一例。临床医生需要了解这种罕见情况，以避免误诊为GIST肿瘤。
