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囊外与囊内髋部骨折的“隐匿性”术前失血:有何差异?

"Hidden" Preoperative Blood Loss With Extracapsular Versus Intracapsular Hip Fractures: What Is the Difference?

作者信息

Harper Katharine D, Navo Paul, Ramsey Frederick, Jallow Sainabou, Rehman Saqib

机构信息

Department of Orthopaedic Surgery and Sports Medicine, Temple University Hospital, Philadelphia PA, USA.

Lewis Katz School of Medicine at Temple University, Temple University School of Medicine, Philadelphia PA, USA.

出版信息

Geriatr Orthop Surg Rehabil. 2017 Dec;8(4):202-207. doi: 10.1177/2151458517729615. Epub 2017 Nov 22.

DOI:10.1177/2151458517729615
PMID:29318081
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5755838/
Abstract

PURPOSE

Excessive blood loss with hip fracture management has been shown to result in increased rates of complications. Our goal is to compare blood loss and transfusion rates between patients with intracapsular and extracapsular (both intertrochanteric (IT) and subtrochanteric (ST)) hip fractures.

METHODS

472 patients were evaluated over a five-year period. Those who presented to the hospital with a proximal femur fracture (femoral neck, IT or ST) were considered for the study. Exclusion criteria included polytrauma, gunshot injuries, periprosthetic fractures, and non-operative management. Primary endpoint was hemoglobin (Hgb) drop from admission to day of surgery (DOS); secondary endpoint was need for pre-op transfusion and discharge location.

RESULTS

304 patients were analyzed who sustained a proximal femur fracture. Median IC Hgb drop was 0.6g/dL; median EC Hgb drop was 1.1g/dL from admission to DOS ( = 0.0272). Rate of pre-operative transfusions was higher in EC (36/194 = 18.6%) than IC fractures (5/105 = 4.5%) ( = 0.0006), and overall transfusion rates remained higher throughout hospital stay (55.7% EC vs. 32.7% IC; = 0.0001). Breakdown of bleeding rate and tranfusion rates between IT and ST fractures were not significant ( = 0.07; = 0.4483). Extracapsular hip fractures were more likely to be discharged to a skilled nursing facility (SNF) (84.4% EC vs. 73.8% IC; = 0.027).

CONCLUSION

Intracapsular hip fractures have significantly less pre-operative blood loss and fewer pre-operative transfusions than their extracapsular counterparts. These findings can be used to establish appropriate pre-operative resuscitative efforts, ensuring that hip fracture protocols account for the increased likelihood of blood loss in extracapsular fractures.

摘要

目的

研究表明,髋部骨折治疗过程中失血过多会导致并发症发生率增加。我们的目标是比较囊内和囊外(包括转子间骨折和转子下骨折)髋部骨折患者的失血量和输血率。

方法

在五年期间对472例患者进行了评估。那些因股骨近端骨折(股骨颈、转子间或转子下骨折)入院的患者被纳入研究。排除标准包括多发伤、枪伤、假体周围骨折和非手术治疗。主要终点是从入院到手术日(DOS)血红蛋白(Hgb)的下降;次要终点是术前输血需求和出院地点。

结果

对304例股骨近端骨折患者进行了分析。从入院到手术日,囊内骨折患者Hgb的中位数下降为0.6g/dL;囊外骨折患者为1.1g/dL(P = 0.0272)。囊外骨折患者术前输血率(36/194 = 18.6%)高于囊内骨折患者(5/105 = 4.5%)(P = 0.0006),并且在整个住院期间总体输血率仍然较高(囊外骨折为55.7%,囊内骨折为32.7%;P = 0.0001)。转子间骨折和转子下骨折之间的出血率和输血率差异无统计学意义(P = 0.07;P = 0.4483)。囊外髋部骨折患者更有可能被转至专业护理机构(SNF)(囊外骨折为84.4%,囊内骨折为73.8%;P = 0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/3e66230b0f3c/10.1177_2151458517729615-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/e6ac3bf693c2/10.1177_2151458517729615-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/1b58d7e7cf74/10.1177_2151458517729615-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/3e66230b0f3c/10.1177_2151458517729615-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/e6ac3bf693c2/10.1177_2151458517729615-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/1b58d7e7cf74/10.1177_2151458517729615-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1e/5755838/3e66230b0f3c/10.1177_2151458517729615-fig3.jpg

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本文引用的文献

1
A systematic review of pre-operative anaemia and blood transfusion in patients with fractured hips.髋关节骨折患者术前贫血和输血的系统评价。
Anaesthesia. 2015 Apr;70(4):483-500. doi: 10.1111/anae.12978.
2
Preoperative factors associated with red blood cell transfusion in hip fracture patients.与髋部骨折患者红细胞输注相关的术前因素。
Arch Orthop Trauma Surg. 2014 Mar;134(3):375-82. doi: 10.1007/s00402-013-1906-3. Epub 2013 Dec 12.
3
Routine blood tests as predictors of mortality in hip fracture patients.
初次及翻修肩关节置换术中的输血趋势及危险因素:单中心分析
Int Orthop. 2025 Jul 10. doi: 10.1007/s00264-025-06605-1.
4
Postoperative outcomes in patients operated for extra- and intracapsular hip fractures - a secondary analysis of two randomized controlled trials.行髋关节囊外和囊内骨折手术患者的术后结局——两项随机对照试验的二次分析
BMC Musculoskelet Disord. 2025 Feb 22;26(1):182. doi: 10.1186/s12891-025-08404-6.
5
The incidence and risk factors of perioperative recurrent stroke in elderly patients with previous ischemic stroke receiving hip fracture surgery.老年缺血性脑卒中患者髋关节骨折术后围手术期复发性脑卒中的发生率及相关危险因素分析。
BMC Musculoskelet Disord. 2024 Aug 10;25(1):636. doi: 10.1186/s12891-024-07753-y.
6
Rate of Complications after Hip Fractures Caused by Prolonged Time-to-Surgery Depends on the Patient's Individual Type of Fracture and Its Treatment.因手术时间延长导致的髋部骨折后并发症发生率取决于患者个体的骨折类型及其治疗方式。
J Pers Med. 2023 Oct 8;13(10):1470. doi: 10.3390/jpm13101470.
7
Subtype consideration in hip fracture research: patient variances in inter- and intra-classification levels highlight the need for future research deliberation. A 2-years follow-up prospective-historical cohort.在髋部骨折研究中考虑亚型:分类内和分类间的患者差异突出了未来研究审议的必要性。一项为期 2 年的前瞻性历史队列研究。
Arch Osteoporos. 2023 Sep 29;18(1):123. doi: 10.1007/s11657-023-01334-7.
8
Bone Cement Implantation Syndrome: A Rare Disaster Following Cemented Hip Arthroplasties-Clinical Considerations Supported by Case Studies.骨水泥植入综合征:骨水泥型髋关节置换术后罕见的严重并发症——基于病例研究的临床思考
J Pers Med. 2023 Sep 15;13(9):1381. doi: 10.3390/jpm13091381.
9
Correlation between Inflammatory Systemic Biomarkers and Surgical Trauma in Elderly Patients with Hip Fractures.老年髋部骨折患者炎症系统生物标志物与手术创伤的相关性
J Clin Med. 2023 Aug 6;12(15):5147. doi: 10.3390/jcm12155147.
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Effect of Peri-Operative Blood Transfusion on Short and Long-Term Mortality Rates in Elderly Patients With Neck of Femur Fractures: A Retrospective Study.围手术期输血对老年股骨颈骨折患者短期和长期死亡率的影响:一项回顾性研究
Cureus. 2023 May 10;15(5):e38825. doi: 10.7759/cureus.38825. eCollection 2023 May.
Injury. 2013 Nov;44(11):1659. doi: 10.1016/j.injury.2013.03.026. Epub 2013 Apr 16.
4
Medical management in the acute hip fracture patient: a comprehensive review for the internist.急性髋部骨折患者的医疗管理:内科医生综合综述
Ochsner J. 2012 Summer;12(2):101-10.
5
Haemoglobin predicts length of hospital stay after hip fracture surgery in older patients.血红蛋白可预测老年髋部骨折手术后的住院时间。
Maturitas. 2012 Jul;72(3):225-8. doi: 10.1016/j.maturitas.2012.03.016. Epub 2012 Apr 21.
6
Liberal or restrictive transfusion in high-risk patients after hip surgery.髋关节手术后高危患者的自由输血或限制性输血。
N Engl J Med. 2011 Dec 29;365(26):2453-62. doi: 10.1056/NEJMoa1012452. Epub 2011 Dec 14.
7
On admission haemoglobin in patients with hip fracture.入院时髋部骨折患者的血红蛋白。
Injury. 2011 Feb;42(2):167-70. doi: 10.1016/j.injury.2010.07.239.
8
The hidden blood loss after hip fracture.髋部骨折后的隐性失血。
Injury. 2011 Feb;42(2):133-5. doi: 10.1016/j.injury.2010.02.015. Epub 2010 Mar 16.
9
Prognostic impact of hemoglobin drop during hospital stay in patients with acute coronary syndromes.急性冠脉综合征患者住院期间血红蛋白下降的预后影响
Rev Port Cardiol. 2009 Apr;28(4):383-95.
10
Anaemia impedes functional mobility after hip fracture surgery.贫血会妨碍髋部骨折手术后的功能性活动能力。
Age Ageing. 2008 Mar;37(2):173-8. doi: 10.1093/ageing/afm161.