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Toxicokinetics of Metformin During Hemodialysis.

作者信息

Ayoub Paul, Hétu Pierre-Olivier, Cormier Monique, Benoit Alexandre, Palumbo Andrea, Dubé Marie-Claude, Gosselin Sophie, Ghannoum Marc

机构信息

Biochemistry Department, University of Montreal Health Center, University of Montreal, Montreal, Quebec, Canada.

Department of Nephrology, Verdun Hospital, University of Montreal, Montreal, Quebec, Canada.

出版信息

Kidney Int Rep. 2017 Mar 7;2(4):759-762. doi: 10.1016/j.ekir.2017.02.017. eCollection 2017 Jul.

DOI:10.1016/j.ekir.2017.02.017
PMID:29318220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5720532/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/862a/5720532/1a9a328d5d9e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/862a/5720532/1a9a328d5d9e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/862a/5720532/1a9a328d5d9e/gr1.jpg

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本文引用的文献

1
Extreme lactic acidosis type B associated with metformin treatment.与二甲双胍治疗相关的B型极重度乳酸性酸中毒
NDT Plus. 2011 Dec;4(6):399-401. doi: 10.1093/ndtplus/sfr110. Epub 2011 Sep 14.
2
Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup.体外治疗二甲双胍中毒：来自体外中毒治疗工作组的系统评价和建议。
Crit Care Med. 2015 Aug;43(8):1716-30. doi: 10.1097/CCM.0000000000001002.
3
Mortality rate in so-called "metformin-associated lactic acidosis": a review of the data since the 1960s.
Kidney Int Rep. 2020 Jun 18;5(9):1525-1528. doi: 10.1016/j.ekir.2020.06.009. eCollection 2020 Sep.
4
A Case Report on Metformin-Associated Lactic Acidosis and Transient Blindness.一例二甲双胍相关乳酸酸中毒及短暂失明的病例报告
Cureus. 2020 Jul 21;12(7):e9325. doi: 10.7759/cureus.9325.
5
A Pharmacokinetic Analysis of Hemodialysis for Metformin-Associated Lactic Acidosis.血液透析治疗二甲双胍相关性乳酸酸中毒的药代动力学分析。
J Med Toxicol. 2021 Jan;17(1):70-74. doi: 10.1007/s13181-020-00802-7. Epub 2020 Aug 12.
6
The pharmacokinetics of metformin in patients receiving intermittent haemodialysis.接受间歇性血液透析患者中二甲双胍的药代动力学。
Br J Clin Pharmacol. 2020 Jul;86(7):1430-1443. doi: 10.1111/bcp.14244. Epub 2020 Feb 25.
7
The Association between Metformin Therapy and Lactic Acidosis.二甲双胍治疗与乳酸性酸中毒的关联。
Drug Saf. 2019 Dec;42(12):1449-1469. doi: 10.1007/s40264-019-00854-x.
8
'Massive' metformin overdose.大剂量二甲双胍服用过量。
Br J Clin Pharmacol. 2018 Dec;84(12):2923-2927. doi: 10.1111/bcp.13582. Epub 2018 Apr 17.
所谓“二甲双胍相关乳酸酸中毒”的死亡率：对20世纪60年代以来数据的综述
Pharmacoepidemiol Drug Saf. 2014 Nov;23(11):1123-7. doi: 10.1002/pds.3689. Epub 2014 Jul 31.
4
Acute metformin intoxication: 2012 experience of Emergency Departement of Lodi, Italy.急性二甲双胍中毒：意大利洛迪急诊科2012年的经验
Clin Chem Lab Med. 2014 Oct;52(10):1489-97. doi: 10.1515/cclm-2014-0208.
5
Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy.二甲双胍蓄积：66 例慢性治疗患者回顾性病例系列中乳酸酸中毒和高血浆二甲双胍水平。
Clin Toxicol (Phila). 2014 Feb;52(2):129-35. doi: 10.3109/15563650.2013.860985. Epub 2013 Nov 28.
6
Pediatric toxicology: specialized approach to the poisoned child.儿科毒理学：中毒儿童的专业处理方法。
Emerg Med Clin North Am. 2014 Feb;32(1):29-52. doi: 10.1016/j.emc.2013.09.008. Epub 2013 Nov 7.
7
The prognostic value of blood pH and lactate and metformin concentrations in severe metformin-associated lactic acidosis.血液pH值、乳酸及二甲双胍浓度在严重二甲双胍相关性乳酸性酸中毒中的预后价值
BMC Pharmacol Toxicol. 2013 Apr 12;14:22. doi: 10.1186/2050-6511-14-22.
8
Toxicokinetics of metformin-associated lactic acidosis with continuous renal replacement therapy.二甲双胍相关乳酸酸中毒与持续肾脏替代治疗的毒代动力学
Eur J Drug Metab Pharmacokinet. 2012 Dec;37(4):249-53. doi: 10.1007/s13318-012-0104-y. Epub 2012 Aug 29.
9
Rapid recovery from acute kidney injury in a patient with metformin-associated lactic acidosis and hypothermia.一名患有二甲双胍相关性乳酸性酸中毒和体温过低的患者急性肾损伤后迅速康复。
Am J Med. 2012 Feb;125(2):e1-2. doi: 10.1016/j.amjmed.2011.06.016.
10
Metformin intoxication requiring dialysis.需要透析的二甲双胍中毒
Hemodial Int. 2011 Oct;15 Suppl 1:S68-71. doi: 10.1111/j.1542-4758.2011.00605.x.