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使用氧化石墨烯作为多相催化剂合成功能化的二氢-2-氧代吡咯。

Synthesis of functionalized dihydro-2-oxopyrroles using graphene oxide as heterogeneous catalyst.

机构信息

Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran.

出版信息

Mol Divers. 2018 Aug;22(3):561-573. doi: 10.1007/s11030-017-9809-9. Epub 2018 Jan 9.

DOI:10.1007/s11030-017-9809-9
PMID:29318444
Abstract

A mild, efficient synthetic approach for the synthesis of highly functionalized dihydro-2-oxopyrroles is developed by using graphene oxide, a readily available and inexpensive material, as an eco-benign solid acid catalyst in ethanol at room temperature. The present methodology displays several advantages such as practical simplicity, high atom economy, easy workup procedure, and high yields of the products.

摘要

一种温和、高效的合成高度官能化二氢-2-氧代吡咯的方法被开发出来,使用氧化石墨烯(一种易得且廉价的材料)作为环境友好的固体酸催化剂,在乙醇中于室温下进行反应。本方法具有操作简单、原子经济性高、后处理简单和产物收率高等优点。

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