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醒脑开窍针刺法联合高压氧治疗缺氧缺血性脑病的临床观察及其对血液流变学的影响

["Xingnao Kaiqiao" Acupuncture(Acupuncture Technique for Restoring Consciousness) Combined with Hyperbaric Oxygen in Patients with Hypoxic Ischemic Encephalopathy: Clinical Observation and Its Influence on Blood Rheology].

作者信息

Zhang Sheng-Yu, Liu Shao-Bing, Xie Hong-Wu, Chen Yi-Min, Liao Kang-Lin, Xiang Yong, Pan Dun

机构信息

Rehabilitation Department of Minda Hospital Affiliated to Hubei University for Nationalities, Enshi 445000, Hubei Province, China.

The Affiliated Hospital to Jiangxi University of Traditional Chinese Medicine, Nanchang 330006.

出版信息

Zhen Ci Yan Jiu. 2017 Dec 25;42(6):518-21. doi: 10.13702/j.1000-0607.2017.06.010.

Abstract

OBJECTIVE

To observe the effect of "Xingnao Kaiqiao" acupuncture(acupuncture technique for restoring consciousness) combined with hyperbaric oxygen in patients with hypoxic ischemic encephalopathy and assess its influence on blood rheology.

METHODS

Forty patients with hypoxic ischemic encephalopathy were randomly divided into treatment group and control group with 20 cases in each group. The treatment group received "Xingnao Kaiqiao" acupuncture combined with hyperbaric oxygen, and the control group received hyperbaric oxygen only. The two groups of patients were treated once per day for 6 consecutive days, which consisted of one course of treatment, and the total treatment lasted for four courses. Before and after treatment, the patients underwent the mini mental state examination (MMSE) to evaluate cognitive function and the barthel index score for activities of daily living. The changes of whole blood viscosity, plasma viscosity, and erythrocyte aggregation index were determined.

RESULTS

After treatment, both the treatment and control groups showed improvements in cognitive function,activities of daily living, and blood rheology compared with those before treatment (<0.05). However, these improvements in the treatment group were significantly greater than those in the control group (<0.05).

CONCLUSIONS

Application of "Xingnao Kaiqiao" acupuncture combined with hyperbaric oxygen in patients with hypoxic ischemic encephalopathy can result in an integrated curative effect, a significant improvement in the blood rheology indexes, and promote the recovery of brain cells.

摘要

目的

观察醒脑开窍针刺法(醒脑复苏针刺技术)联合高压氧治疗对缺氧缺血性脑病患者的疗效,并评估其对血液流变学的影响。

方法

将40例缺氧缺血性脑病患者随机分为治疗组和对照组,每组20例。治疗组采用醒脑开窍针刺法联合高压氧治疗,对照组仅采用高压氧治疗。两组患者均每天治疗1次,连续治疗6天为1个疗程,共治疗4个疗程。治疗前后,患者接受简易精神状态检查表(MMSE)评估认知功能,并进行日常生活活动能力巴氏指数评分。测定全血黏度、血浆黏度和红细胞聚集指数的变化。

结果

治疗后,治疗组和对照组的认知功能、日常生活活动能力及血液流变学指标均较治疗前有所改善(P<0.05)。然而,治疗组的这些改善明显大于对照组(P<0.05)。

结论

醒脑开窍针刺法联合高压氧治疗缺氧缺血性脑病患者可产生综合疗效,显著改善血液流变学指标,促进脑细胞恢复。

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