与足月低体重儿出生相关的因素：来自巴基斯坦农村地区的一项匹配病例对照研究。

Factors associated with low birthweight in term pregnancies: a matched case-control study from rural Pakistan.

机构信息

Department of Obstetrics, Gynecology and Neonatology, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Women and Child Health Division, Aga Khan University, Karachi, Pakistan.

Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia.

出版信息

East Mediterr Health J. 2018 Jan 2;23(11):754-763. doi: 10.26719/2017.23.11.754.

DOI:10.26719/2017.23.11.754

PMID:29319147

Abstract

Low birthweight (LBW) remains a significant public health problem in Pakistan and further understanding of factors associated with LBW is required. We conducted a hospital-based matched case control study to identify risk factors associated with LBW in a rural district of Pakistan. We found that illiteracy (AOR: 2.68; 95% CI: 1.59 - 4.38), nulliparity (AOR: 1.82; 95% CI: 1.26-2.44), having a previous miscarriage/abortion (AOR: 1.22; 95% CI: 1.06-2.35), having < 2 antenatal care (ANC) visits during last pregnancy (AOR: 2.43; 95% CI: 1.34-2.88), seeking ANC in third trimester (AOR: 3.62; 95% CI : 2.14-5.03), non-use of iron folic acid during last pregnancy (AOR: 2.72; 95% CI: 1.75-3.17), having hypertension during last pregnancy (AOR: 1.42; 95% CI: 1.13-2.20), being anemic (AOR: 2.67; 95% CI: 1.65-5.24) and having postpartum weight of <45 kg (AOR: 3.30; 95% CI : 1.97-4.52) were significantly associated with an increased odds of having a LBW baby. Our study identifies modifiable risk factors requiring immediate commitment from the health authorities.

摘要

低出生体重（LBW）仍然是巴基斯坦一个重大的公共卫生问题，需要进一步了解与 LBW 相关的因素。我们进行了一项基于医院的匹配病例对照研究，以确定巴基斯坦农村地区与 LBW 相关的风险因素。我们发现，文盲（OR：2.68；95%CI：1.59-4.38）、未婚（OR：1.82；95%CI：1.26-2.44）、有过流产/堕胎史（OR：1.22；95%CI：1.06-2.35）、上次妊娠时接受的产前护理（ANC）次数<2 次（OR：2.43；95%CI：1.34-2.88）、在妊娠晚期接受 ANC（OR：3.62；95%CI：2.14-5.03）、上次妊娠时未使用铁叶酸（OR：2.72；95%CI：1.75-3.17）、上次妊娠时患有高血压（OR：1.42；95%CI：1.13-2.20）、贫血（OR：2.67；95%CI：1.65-5.24）和产后体重<45 公斤（OR：3.30；95%CI：1.97-4.52）与 LBW 婴儿的发生几率增加显著相关。我们的研究确定了需要卫生当局立即关注的可改变的风险因素。