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与埃塞俄比亚中北部Shewa 区低出生体重相关的因素:病例对照研究。

Factors associated with low birthweight in North Shewa zone, Central Ethiopia: case-control study.

机构信息

Department of Public Health, Selale University, Salale, Ethiopia.

School of Public Health, Hawassa University, Hawassa, Ethiopia.

出版信息

Ital J Pediatr. 2018 Jul 4;44(1):76. doi: 10.1186/s13052-018-0516-7.

Abstract

BACKGROUND

Low birthweight (LBW) is an important predictor of neonatal and post neonatal child morality. Though its risk factors have been extensively studied in the developed world; limited epidemiological evidence is available in developing countries including Ethiopia. The purpose of the study is to determine the risk factors of LBW in North Shewa zone, Central Ethiopia.

METHODS

Unmatched case-control study involving 94 cases and 376 controls was conducted from Jan to Mar 2017 in three public hospitals in the zone. A case was defined as a singleton live birth with birthweight less than 2.5 kg; whereas, a control was a newborn that weighs 2.5-4.0 kg. Cases and controls were recruited on an ongoing basis until the required sample sizes were fulfilled. Data were collected by interviewing mothers, reviewing medical records and measuring the anthropometry of the mothers and the newborns. Bivariable and multivariable logistic regression analyses were used to identify risk factors of LBW. The outputs of the analyses are presented using adjusted odds ratio (AOR) with the respective 95% confidence interval (CI).

RESULTS

Mothers with no formal education had two times increased odds of delivering LBW babies than women with formal education [AOR = 2.20 (95% CI: 1.11, 4.38)]. Mothers with no history of nutrition counseling during pregnancy had three times increased odds of giving LBW babies than those who were counseled [AOR = 3.35 (95% CI: 1.19, 9.43)]. Non-married women had higher odds of giving LBW newborns as compared to married ones [AOR = 3.54 (95% CI: 1.83, 6.83)]. Mothers from food insecure households had about four times higher odds of LBW as compared to food secure mothers [AOR = 4.42 (95% CI: 1.02,22.25)]. In contrast to mothers who had the recommended four or more antenatal care (ANC) visits, those who were not booked had three times increased odds of giving to LBW baby [AOR = 3.03 (95% CI: 1.19,7.69)].

CONCLUSION

Improving the socio-economic status of mothers, enhancing the utilization of ANC and strengthening the integration of nutrition counseling into ANC help to reduce LBW.

摘要

背景

低出生体重(LBW)是新生儿和后期儿童死亡率的重要预测指标。尽管在发达国家已经广泛研究了其危险因素,但在包括埃塞俄比亚在内的发展中国家,只有有限的流行病学证据。本研究的目的是确定埃塞俄比亚中北部 Shewa 地区 LBW 的危险因素。

方法

2017 年 1 月至 3 月期间,在该地区的三家公立医院中,进行了一项未匹配的病例对照研究,共纳入 94 例病例和 376 例对照。病例定义为出生体重低于 2.5kg 的单胎活产儿;而对照则是出生体重为 2.5-4.0kg 的新生儿。病例和对照持续招募,直到达到所需的样本量。通过访谈母亲、查阅病历和测量母亲和新生儿的人体测量学数据来收集数据。采用单变量和多变量逻辑回归分析来确定 LBW 的危险因素。分析结果以校正比值比(AOR)及其相应的 95%置信区间(CI)表示。

结果

未接受正规教育的母亲分娩 LBW 婴儿的几率是接受正规教育的母亲的两倍[校正比值比(AOR)=2.20(95%置信区间:1.11-4.38)]。在怀孕期间没有接受营养咨询的母亲分娩 LBW 婴儿的几率是接受咨询的母亲的三倍[AOR=3.35(95%置信区间:1.19-9.43)]。与已婚母亲相比,未婚母亲分娩 LBW 新生儿的几率更高[AOR=3.54(95%置信区间:1.83-6.83)]。来自粮食不安全家庭的母亲发生 LBW 的几率是粮食安全母亲的四倍[AOR=4.42(95%置信区间:1.02-22.25)]。与接受了推荐的四次或更多次产前保健(ANC)的母亲相比,未预约的母亲分娩 LBW 婴儿的几率增加了两倍[AOR=3.03(95%置信区间:1.19-7.69)]。

结论

提高母亲的社会经济地位、增加 ANC 的利用以及加强营养咨询与 ANC 的整合有助于降低 LBW。

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