Bianchi A T, Hussaarts-Odijk L M, Bril H, de Ruiter H, Benner R
Adv Exp Med Biol. 1985;186:521-9. doi: 10.1007/978-1-4613-2463-8_64.
We investigated whether the long-lasting state of nonresponsiveness that is induced by intravenous immunization with alloantigens is mediated by suppressor T cells, or is caused by inactivation or deletion of the relevant alloreactive T cell clones. The data from parabiosis and thoracic duct drainage experiments suggest that the state of nonresponsiveness depends on recirculating non-proliferating Ts memory cells.
我们研究了同种异体抗原静脉注射诱导的长期无反应状态是由抑制性T细胞介导的，还是由相关同种异体反应性T细胞克隆的失活或缺失引起的。联体生活和胸导管引流实验的数据表明，无反应状态取决于循环中的非增殖性Ts记忆细胞。
