Higuchi Yoshihiro, Kimoto Yasutaka, Tanoue Rika, Tokunou Tomotake, Tomonari Kenichiro, Maeda Toyoki, Horiuchi Takahiko
Department of Internal Medicine, Kyushu University Beppu Hospital, Japan.
Department of Radiology, Oita Diagnostic Imaging Center, Japan.
Intern Med. 2018 Jun 1;57(11):1601-1604. doi: 10.2169/internalmedicine.9652-17. Epub 2018 Jan 11.
We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.
我们在此报告一例通过F-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)检测到的并发心脏结节病和大血管性主动脉炎,并在免疫抑制治疗期间进行了随访。给予大剂量泼尼松龙(1 mg/kg)后,系列FDG-PET显示心脏和心外区域几乎所有异常的FDG摄取,包括从腹部到双侧髂动脉,均已消失。在泼尼松龙逐渐减量期间,需要加用甲氨蝶呤治疗心脏结节病的复发。FDG-PET是检测合并大血管性主动脉炎的心脏结节病以及监测免疫抑制治疗效果的有用工具。