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三级医疗中心2型糖尿病患者中阻塞性睡眠呼吸暂停的高患病率

High Prevalence of Obstructive Sleep Apnea among People with Type 2 Diabetes Mellitus in a Tertiary Care Center.

作者信息

Viswanathan Vijay, Ramalingam Indira Priyadarshini, Ramakrishnan Nagarajan

机构信息

Head & Chief Diabetologist, M.V. Hospital for Diabetes & President, Prof. M. Viswanathan Diabetes Research Centre, Chennai, Tamil Nadu.

Clinical Research Associate, Prof. M. Viswanathan Diabetes Research Centre, Chennai, Tamil Nadu.

出版信息

J Assoc Physicians India. 2017 Nov;65(11):38-42.

Abstract

PURPOSE

Untreated obstructive sleep apnea (OSA) is a risk factor for hypertension and cardiac events, and is associated with increased mortality. Recent studies indicate that majority of people with type 2 diabetes also has OSA. The aim of this study was to assess the prevalence and severity of OSA and risk factors contributing to it among people with chronic and severe type 2 diabetes.

METHODS

A total of 203 people with type 2 diabetes (mean age: 54±8 years, 145 males, 58 females, HbA1c ≥7% [53mmol/mol]) attending a diabetes specialty hospital were included in the study; all were subjected to comprehensive diabetic evaluation and Apnea Hypopnea Index (AHI) was used to evaluate OSA.

RESULTS

23.65% of the study subjects had OSA (AHI ≥15). OSA was more prevalent among men compared to women. BMI, was significantly higher among subjects with OSA (P=0.01). People with OSA had higher percentage of diabetic complications such as cardiovascular disease (CVD), retinopathy and neuropathy. Hypertension was identified as independent predictors of OSA.

CONCLUSIONS

Prevalence of OSA was higher in this study compared to Indian studies hitherto. Since OSA is treatable, people with diabetes should be screened for this condition to reduce their CVD risk.

摘要

目的

未经治疗的阻塞性睡眠呼吸暂停(OSA)是高血压和心脏事件的危险因素,并与死亡率增加相关。最近的研究表明,大多数2型糖尿病患者也患有OSA。本研究的目的是评估慢性重度2型糖尿病患者中OSA的患病率、严重程度及其危险因素。

方法

本研究纳入了一家糖尿病专科医院的203例2型糖尿病患者(平均年龄:54±8岁,男性145例,女性58例,糖化血红蛋白≥7%[53mmol/mol]);所有患者均接受了全面的糖尿病评估,并采用呼吸暂停低通气指数(AHI)评估OSA。

结果

23.65%的研究对象患有OSA(AHI≥15)。与女性相比,OSA在男性中更为普遍。OSA患者的体重指数(BMI)显著更高(P=0.01)。OSA患者患有糖尿病并发症如心血管疾病(CVD)、视网膜病变和神经病变的比例更高。高血压被确定为OSA的独立预测因素。

结论

与迄今为止的印度研究相比,本研究中OSA的患病率更高。由于OSA是可治疗的,糖尿病患者应接受该疾病筛查以降低其CVD风险。

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