Shuteeva T V, Gorshunova N K
Kursk State Medical University, 3, K. Marksa str., Kursk, 305041, Russian Federation;
Adv Gerontol. 2017;30(5):765-769.
In the formation of a common age-associated pathological process in patients with Parkinson's disease along with movement disorders so-called «non-motorized» clinical symptoms (including anxiety and depression) play an important role. These pathological manifestations can reduce the quality of life of the patient and require specific therapeutic measures. The picker is the use of drugs - antidepressants. The article discusses the opportunity for the effective and safe use of such drug - sertraline combined with basic therapy, which is widely used in Parkinson's disease. Distinct positive results were obtained in the process of using the proposed scheme of treatment in 35 patients at the age of 62,3±3,6 years and with disease duration of 3,9±2,6 years. We observed decrease depressive symptoms, improve sleep, decrease anxiety levels while improving the quality of life of patients. No unwanted side effects of the treatment were observed. The possibility to use of sertraline for the relief of anxiety and depressive disorders in the elderly suffering from Parkinson's disease was shown.
在帕金森病患者中,除了运动障碍外,一种常见的与年龄相关的病理过程正在形成,所谓的“非运动性”临床症状(包括焦虑和抑郁)起着重要作用。这些病理表现会降低患者的生活质量,需要采取特定的治疗措施。首选的是使用药物——抗抑郁药。本文讨论了将这种药物——舍曲林与帕金森病广泛使用的基础治疗相结合进行有效和安全使用的可能性。在对35名年龄为62.3±3.6岁、病程为3.9±2.6年的患者使用所提议的治疗方案的过程中,取得了明显的积极效果。我们观察到抑郁症状减轻、睡眠改善、焦虑水平降低,同时患者的生活质量得到提高。未观察到治疗的不良副作用。研究表明,舍曲林可用于缓解患有帕金森病的老年人的焦虑和抑郁障碍。