Sandor P, Shapiro C M
Department of Psychiatry, Toronto Hospital, Ontario, Canada.
J Psychosom Res. 1994;38 Suppl 1:125-39. doi: 10.1016/0022-3999(94)90143-0.
Sleep is invariably disrupted in patients who have depression and in patients with anxiety disorders. Depression and anxiety frequently coexist and are associated with disturbances in various neurotransmitters. The authors explore the relationship between sleep and the two disorders as well as the effects of antidepressants and anxiolytics on sleep architecture. The effects on sleep of various neurotransmitter systems implicated in depression and anxiety are outlined. Lastly, various theoretical models are proposed to account for the above mentioned phenomena and further directions for research are suggested.
抑郁症患者和焦虑症患者的睡眠总是会受到干扰。抑郁症和焦虑症常常并存,且与多种神经递质紊乱有关。作者探讨了睡眠与这两种疾病之间的关系,以及抗抑郁药和抗焦虑药对睡眠结构的影响。概述了与抑郁症和焦虑症相关的各种神经递质系统对睡眠的影响。最后,提出了各种理论模型来解释上述现象,并给出了进一步的研究方向。