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跟骨关节内移位骨折的手术治疗与非手术治疗:随机对照试验的荟萃分析

Operative versus Non operative treatment of displaced intraarticular fracture of calcaneum: a meta-analysis of randomized controlled trials.

作者信息

Meena S, Hooda A, Sharma P, Mittal S, Sharma J, Chowdhury B

出版信息

Acta Orthop Belg. 2017 Dec;83(1):161-169.

Abstract

Various studies comparing operative and non-operative intervention for displaced intrarticular calcaneal fractures have reported conflicting findings in the past. The objective of this meta-analysis was to compare the efficacy and safety of open reduction and internal fixation (ORIF) vis-a-vis conservative management. Relevant randomized controlled trials (RCTs) comparing operative and non-operative intervention for displaced intraarticular calcaneal fractures were assessed and included in this meta-analysis. Data was extracted independently and methodological quality was further assessed. The inclusion criteria of this meta-analysis were: randomized controlled trials comparing operative with non-operative intervention for displaced intra-articular fractures of calcaneum and reporting atleast one of the main outcomes as failure to resume pre-injury work, residual pain and other complications. Eight randomized controlled trials fulfilled the criteria for this meta-analysis. Pooled results showed that patients managed conservatively failed to resume pre-injury work (RR 0.60, 95% CI = 0.37-0.98, P = 0.04). However operative intervention was associated with more complications (RR 1.74, 95% CI = 1.28 to 2.37, P = 0.0005). There was no statistically significant difference in residual pain (RR 0.73 95% CI = 0.40-1.36, P = 0.33) and reoperation (RR = 0.75, 95% CI = 0.48-1.16, P = 0.20) between the two groups. Surgery can benefit patients with calcaneal fracture and increases their likelihood to resume pre-injury work. However, the complication rates are significantly higher in the operative group. Since the included trials have used different scores to measure patient outcomes, hence little effective data could.

摘要

过去,多项比较移位性关节内跟骨骨折手术治疗与非手术治疗的研究报告了相互矛盾的结果。本荟萃分析的目的是比较切开复位内固定术(ORIF)与保守治疗的疗效和安全性。评估了比较移位性关节内跟骨骨折手术治疗与非手术治疗的相关随机对照试验(RCT)并将其纳入本荟萃分析。数据由独立提取,并进一步评估方法学质量。本荟萃分析的纳入标准为:比较跟骨关节内移位骨折手术与非手术治疗的随机对照试验,且至少报告以下主要结局之一:未能恢复伤前工作、残留疼痛及其他并发症。八项随机对照试验符合本荟萃分析的标准。汇总结果显示,接受保守治疗的患者未能恢复伤前工作(RR 0.60,95%CI = 0.37 - 0.98,P = 0.04)。然而,手术干预与更多并发症相关(RR 1.74,95%CI = 1.28至2.37,P = 0.0005)。两组之间在残留疼痛(RR 0.73,95%CI = 0.40 - 1.36,P = 0.33)和再次手术(RR = 0.75,95%CI = 0.48 - 1.16,P = 0.20)方面无统计学显著差异。手术可使跟骨骨折患者受益,并增加其恢复伤前工作的可能性。然而,手术组的并发症发生率明显更高。由于纳入的试验使用了不同的评分来衡量患者结局,因此有效数据很少。

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