State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Si Pai Lou 2, Nanjing 210096, China.
Nanoscale. 2018 Jan 25;10(4):2090-2098. doi: 10.1039/c7nr07225b.
A multifunctional, wearable sensor based on a reduced oxide graphene (rGO) film onto a porous inverse opal acetylcellulose (IOAC) film has been developed and can perform simultaneous, in situ monitoring of various human motions and ion concentrations in sweat. The rGO film is used as a strain-sensing layer for monitoring human motion via its resistance change, whereas the porous IOAC film is used as a flexible microstructured substrate not only for high sensitive motion sensing, but also for collection and analysis of ion concentrations in sweat by its simple colorimetric changes or reflection-peak shifts. Studies on humans demonstrated that the devices have excellent capability for monitoring various human motions, such as finger bending motion, wrist bending motion, head rotation motion and various small-scale motions of the throat. Simultaneous, in situ analysis of the ion concentration in sweat during these motions shows that the IOAC substrate can detect a wide range of NaCl concentrations in sweat from normal 30 to 680 mM under the conditions of severe dehydration. This investigation provides new horizons toward the design and fabrication of multifunctional, wearable health monitoring devices and the proposed wearable sensor shows promising applications in healthcare and preventive medicine.
已经开发出一种基于还原氧化石墨烯 (rGO) 薄膜到多孔反蛋白石醋酸纤维素 (IOAC) 薄膜的多功能可穿戴传感器，可同时原位监测各种人体运动和汗液中的离子浓度。rGO 薄膜用作应变传感层，通过其电阻变化来监测人体运动，而多孔 IOAC 薄膜不仅用作灵活的微结构基底，用于高灵敏运动感应，还用于通过简单的比色变化或反射峰位移来收集和分析汗液中的离子浓度。对人类的研究表明，该设备具有监测各种人体运动的优异能力，例如手指弯曲运动、手腕弯曲运动、头部旋转运动和喉咙的各种小范围运动。同时，在这些运动过程中对汗液中离子浓度的原位分析表明，在严重脱水的情况下，IOAC 基底可以检测到从正常 30 到 680mM 的汗液中广泛的 NaCl 浓度。这项研究为多功能可穿戴健康监测设备的设计和制造提供了新的视野，所提出的可穿戴传感器在医疗保健和预防医学中具有广阔的应用前景。
