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神经源性口吃:文献综述

Neurogenic stuttering: a review of the literature.

作者信息

Cruz C, Amorim H, Beca G, Nunes R

机构信息

Hospital de Braga, Braga, Portugal.

Centro Hospitalar S. Joao, Porto, Portugal.

出版信息

Rev Neurol. 2018 Jan 16;66(2):59-64.

Abstract

INTRODUCTION

Neurogenic stuttering is a disorder of neurologic origin in the rhythm of speech during which the patient knows exactly what he wants to say but is unable to because of an involuntary prolongation, cessation or repetition of a sound.

AIM

To assemble new insights regarding the epidemiology, pathophysiology, diagnosis, evaluation and treatment of neurogenic stuttering.

DEVELOPMENT

A review of all PubMed and Scopus published articles between January 2000 and September 2016 was performed. Thirty-three publications were analyzed. Neurogenic stuttering is a rare entity whose epidemiological incidence is yet not fully established. It is correlated with several neurological diseases and with several possible localizations within the nervous system. Notwithstanding the recent advances in the understanding of the underlying mechanism, it is not yet possible to establish a single pathophysiological mechanism of neurogenic stuttering. The differential diagnosis is complex and requires the detailed knowledge of other language disorders. The treatment is currently based on specific speech language therapy strategies.

CONCLUSION

Neurogenic stuttering is a complex disorder which is not fully understood. Additional studies might help to better explain the underlying pathophysiological mechanism and to open doors to novel therapeutic methods.

摘要

引言

神经性口吃是一种源于神经系统的言语节律障碍,在此期间患者确切知道自己想说什么,但由于声音的不自主延长、停顿或重复而无法表达。

目的

收集有关神经性口吃的流行病学、病理生理学、诊断、评估和治疗的新见解。

进展

对2000年1月至2016年9月期间在PubMed和Scopus上发表的所有文章进行了综述。分析了33篇出版物。神经性口吃是一种罕见的病症,其流行病学发病率尚未完全确定。它与几种神经系统疾病以及神经系统内的几种可能定位相关。尽管在对潜在机制的理解方面取得了最新进展,但尚无法确定神经性口吃的单一病理生理机制。鉴别诊断很复杂,需要详细了解其他语言障碍。目前的治疗基于特定的言语语言治疗策略。

结论

神经性口吃是一种尚未完全理解的复杂病症。更多的研究可能有助于更好地解释潜在的病理生理机制,并为新的治疗方法打开大门。

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