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经皮内镜胃造口部位的头颈部癌症肿瘤种植。

Head and Neck Cancer Tumor Seeding at the Percutaneous Endoscopic Gastrostomy Site.

机构信息

Coram CVS Specialty Infusion Services, Denver, Colorado, USA.

出版信息

Nutr Clin Pract. 2018 Feb;33(1):73-80. doi: 10.1002/ncp.10021. Epub 2018 Jan 11.

DOI:10.1002/ncp.10021
PMID:29323421
Abstract

The National Institutes of Health National Cancer Institute estimates that over 13,000 new cases of head and neck cancer (HNC) will be diagnosed in 2017. Patients with HNC often require enteral nutrition (EN) via gastrostomy tube to provide nutrition support and hydration because of tumor obstruction of the oropharynx and/or cumulative effects of chemoradiation therapy. The percutaneous endoscopic gastrostomy (PEG) tube has become the preferred technique for EN access because placement is considered a minimally invasive procedure. There are 3 methods of PEG placement: Gauderer-Ponsky "pull," Sachs-Vine "push," and Russell "push" method. The Gauderer-Ponsky "pull" method has become the preferred method of PEG placement. It has been previously reported that the rate of stomal metastasis can be 0.5%-1% of those undergone the Gauderer-Ponsky "pull" method that is consistent with HNC morphology. Other researchers believe the rate may be as high as 0.5%-3%. This article reviews the 3 methods of PEG placement, as well as all potential complications, including metastatic seeding at the PEG site. In addition, 1 additional case of tumor seeding at the PEG site will be reviewed. Consideration for avoidance of the Gauderer-Ponsky pull method of PEG placement or other methods of feeding tube placement where the gastrostomy tube has to pass through the oral cavity before exiting the abdominal wall in patients with squamous cell carcinoma of the head and neck should be considered.

摘要

美国国立卫生研究院国家癌症研究所估计,2017 年将有超过 13000 例头颈部癌症(HNC)新发病例。由于口咽肿瘤阻塞和/或放化疗的累积效应,HNC 患者常需要经胃造口管进行肠内营养(EN)以提供营养支持和水合作用。经皮内镜胃造口术(PEG)管已成为 EN 通路的首选技术,因为其放置被认为是一种微创程序。PEG 放置有 3 种方法:Gauderer-Ponsky“拉”、Sachs-Vine“推”和 Russell“推”法。Gauderer-Ponsky“拉”法已成为 PEG 放置的首选方法。先前有报道称,Gauderer-Ponsky“拉”法的吻合口转移率为 0.5%-1%,与 HNC 形态一致。其他研究人员认为,转移率可能高达 0.5%-3%。本文回顾了 PEG 放置的 3 种方法以及所有潜在的并发症,包括吻合口转移。此外,还将回顾 1 例吻合口转移病例。对于头颈部鳞状细胞癌患者,应考虑避免使用 Gauderer-Ponsky 拉式 PEG 放置或其他需要经口腔穿出腹壁的胃造口管放置方法。

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Head and Neck Cancer Tumor Seeding at the Percutaneous Endoscopic Gastrostomy Site.经皮内镜胃造口部位的头颈部癌症肿瘤种植。
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