Scofield Virginial, Nagashima Lauren S
Biol Bull. 1983 Dec;165(3):733-744. doi: 10.2307/1541475.
Botryllus rejection reactions were followed in pairs of oozooids placed together immediately after initiation of metamorphosis. Within twelve hours, both compatible and incompatible oozooid pairs underwent tunic fusion and initiation of ampullar tip-to-side contact. Vascular fusion followed within two days between compatible pairs, while the fusion sequence was interrupted in the incompatible pairs by a rapid cytotoxic rejection response. Events occurring within and outside the ampullae in rejections were effector responses whose consequences were separation of the ampullae and isolation of the involved tissues from the bodies of the oozooids. Genetics experiments suggested that the four distinct types of rejection reflect a hierarchy of histoincompatibility in this system.
在变态开始后立即将成对的游动孢子放在一起，观察博特赖斯排斥反应。在12小时内，相容和不相容的游动孢子对都经历了被囊融合和壶腹尖端到侧面接触的开始。两天内相容对之间发生血管融合，而不相容对中的融合序列被快速的细胞毒性排斥反应中断。排斥反应中壶腹内外发生的事件是效应反应，其结果是壶腹分离以及相关组织与游动孢子体分离。遗传学实验表明，四种不同类型的排斥反应反映了该系统中组织不相容性的等级制度。
