Raposio Edoardo, Bortolini Sara, Maistrello Lara, Grasso Donato A
Department of Medicine and Surgery, Plastic Surgery Chair, University of Parma, Parma, Italy; Cutaneous, Mininvasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy.
Department of Life Sciences, University of Modena and Reggio Emilia, Reggio Emilia, Italy.
Wounds. 2017 Dec;29(12):367-373.
Cutaneous ulcers tend to become chronic and have a profound impact on quality of life. These wounds may become infected and lead to greater morbidity and even mortality. In the past, larvae (ie, maggots) of certain common flies (Lucilia sericata and Lucilia cuprina) were considered useful in ulcer management because they only remove necrotic tissue while promoting healthy tissue in the wound bed, thus helping wounds heal faster. Recently, maggots from several other fly species (Calliphora vicina, Calliphora vomitoria, Phormia regina, Chrysomya albiceps, Sarcophaga carnaria, and Hermetia illucens) have been shown in vitro to possess characteristics (ie, debridement efficacy and putative antimicrobial potentialities) that make them suitable candidates for possible use in clinical practice. This review presents a historical analysis of larval debridement and speculates future directions based on the literature presented.
皮肤溃疡往往会发展成慢性，对生活质量产生深远影响。这些伤口可能会感染，导致更高的发病率甚至死亡率。过去，某些常见苍蝇（丝光绿蝇和铜绿蝇）的幼虫（即蛆虫）被认为在溃疡治疗中有用，因为它们只清除坏死组织，同时促进伤口床中的健康组织，从而帮助伤口更快愈合。最近，其他几种苍蝇（红头丽蝇、反吐丽蝇、黑须亚麻蝇、白纹伊蚊、食肉蝇和黑水虻）的蛆虫在体外已显示出具有某些特性（即清创效果和假定的抗菌潜力），使其成为可能用于临床实践的合适候选者。本综述对幼虫清创进行了历史分析，并根据所呈现的文献推测了未来的方向。
