Hôpital Pitié-Salpêtrière, Paris, France.
ASAIO J. 2018 Nov/Dec;64(6):e187-e190. doi: 10.1097/MAT.0000000000000742.
A retrospective review of three patients with acute respiratory distress syndrome (ARDS) and normal baseline right ventricular function admitted to the Cardiac Surgery Intensive Care Unit whom developed acute cor pulmonale while on veno-venous extracorporeal membrane oxygenation. These patients were diagnosed with ARDS using Berlin Criteria definitions and cannulated with a dual lumen (Avalon) cannula. Despite variations in history, presentation, and course, findings of acute cor pulmonale were encountered 4 to 6 weeks after extracorporeal membrane oxygenation cannulation. The potential mechanisms include thromboembolic burden to the pulmonary vasculature, hypoxemia, acidosis, the pathologic progression of ARDS, and chronic nonphysiologic flow to the right heart.
回顾性分析了 3 例急性呼吸窘迫综合征（ARDS）和正常基线右心功能的患者，这些患者在接受静脉-静脉体外膜肺氧合（VV-ECMO）治疗时发生了急性肺心病。这些患者根据柏林标准诊断为 ARDS，并使用双腔（Avalon）导管进行置管。尽管病史、表现和病程存在差异，但在 ECMO 置管后 4 至 6 周时均发现急性肺心病。潜在的机制包括肺血管血栓栓塞负担、低氧血症、酸中毒、ARDS 的病理进展和右心的慢性非生理血流。
