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金黄色葡萄球菌通过上调超氧化物歧化酶 M 和铁摄取蛋白适应囊性纤维化患者气道环境。

Adaptation of Staphylococcus aureus to Airway Environments in Patients With Cystic Fibrosis by Upregulation of Superoxide Dismutase M and Iron-Scavenging Proteins.

机构信息

Institute of Medical Microbiology, Münster.

Institute of Microbiology, Ernst-Moritz-Arndt-University, Greifswald.

出版信息

J Infect Dis. 2018 Apr 11;217(9):1453-1461. doi: 10.1093/infdis/jiy012.

DOI:10.1093/infdis/jiy012
PMID:29325044
Abstract

Adaptation of S. aureus to the hostile environment of CF airways resulted in changed abundance of proteins involved in energy metabolism, cellular processes, transport and binding, but most importantly in an iron-scavenging phenotype and increased activity of superoxide dismutase M.

摘要

金黄色葡萄球菌适应 CF 气道的恶劣环境导致参与能量代谢、细胞过程、运输和结合的蛋白质丰度发生变化，但最重要的是，表现出铁掠夺表型和超氧化物歧化酶 M 的活性增加。

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