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迈向精准医学。

Towards precision medicine.

作者信息

Bardakjian Tanya, Gonzalez-Alegre Pedro

机构信息

Neurogenetics Program, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

Handb Clin Neurol. 2018;147:93-102. doi: 10.1016/B978-0-444-63233-3.00008-7.

Abstract

The concept of precision medicine, also referred to as individualized or personalized medicine, has recently gained traction in scientific, medical, and public spheres, and is frequently mentioned as the next model of healthcare delivery. Its goal is to integrate unique information obtained from a given patient to customize the care provided to achieve the best possible outcome. Although precision medicine is not fully implemented yet, its application is slowly infiltrating clinical practice, and the dream of individualizing healthcare to each patient is now closer to being fulfilled. This chapter summarizes the current status of personalized medicine in the neurology clinic, including precision diagnostics and individualized therapeutics. Subsequently, we address the main hurdles that the healthcare community needs to overcome to expand this model of healthcare delivery and predict how this evolving field will shape future neurologic practice.

摘要

精准医学的概念,也被称为个体化或个性化医学,最近在科学、医学和公共领域获得了广泛关注,并经常被提及为下一种医疗服务模式。其目标是整合从特定患者获得的独特信息,以定制所提供的护理,从而实现最佳可能结果。尽管精准医学尚未完全实施,但其应用正在缓慢渗透到临床实践中,为每位患者实现个性化医疗的梦想现在正越来越接近实现。本章总结了神经科诊所中个性化医学的现状,包括精准诊断和个体化治疗。随后,我们探讨了医疗界为扩大这种医疗服务模式需要克服的主要障碍,并预测这个不断发展的领域将如何塑造未来的神经科实践。

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