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[精准医学的进展:科学视角]

[Progress in precision medicine: a scientific perspective].

作者信息

Wang B, Li L M

机构信息

Health Science Popularization Research Center, Chinese Academy of Medical Sciences, Beijing 100730, China.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jan 10;38(1):1-2. doi: 10.3760/cma.j.issn.0254-6450.2017.01.001.

Abstract

Precision medicine is a new strategy for disease prevention and treatment by taking into account differences in genetics, environment and lifestyles among individuals and making precise diseases classification and diagnosis, which can provide patients with personalized, targeted prevention and treatment. Large-scale population cohort studies are fundamental for precision medicine research, and could produce best evidence for precision medicine practices. Current criticisms on precision medicine mainly focus on the very small proportion of benefited patients, the neglect of social determinants for health, and the possible waste of limited medical resources. In spite of this, precision medicine is still a most hopeful research area, and would become a health care practice model in the future.

摘要

精准医学是一种疾病预防和治疗的新策略,它考虑个体之间在基因、环境和生活方式上的差异,进行精确的疾病分类和诊断,能够为患者提供个性化、针对性的预防和治疗。大规模人群队列研究是精准医学研究的基础,可为精准医学实践提供最佳证据。目前对精准医学的批评主要集中在受益患者比例极小、忽视健康的社会决定因素以及可能造成有限医疗资源的浪费。尽管如此,精准医学仍是一个极具前景的研究领域,并将在未来成为一种医疗保健实践模式。

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