Laboratoire d'explorations fonctionnelles vasculaires, CHU d'Angers, France.
Laboratoire d'explorations fonctionnelles vasculaires, CHU d'Angers, France; Laboratoire de Physiologie, Institut Supérieur des Sciences de la Santé, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Microvasc Res. 2018 May;117:44-49. doi: 10.1016/j.mvr.2018.01.003. Epub 2018 Jan 9.
Transcutaneous oxygen pressure (tcpO2) reliability is blunted by an unpredictable transcutaneous gradient through the skin. We hypothesized that the "Decrease from Rest of Oxygen pressure (DROP: subtraction of limb-changes from chest-changes from the respective starting values) would show a good to excellent reliability during Exercise -tcpO2 investigations.
In three different experiments we tested: The intra-test variability at the peripheral level (Experiment A: 32 patients, 16 at each location), at the chest level (Experiment B: 45 patients) and the test-retest reproducibility within 3 months (Experiment C: 67 patients). We calculated the intra-class coefficient of correlation (ICC) with 95% confidence interval [Lower/upper limit]. ICC between 0.60 and 0.749 indicate a good agreement. ICC above 0.750 indicates an excellent agreement.
ICC values for DROP-min were 0.848 [0.723/0.935] at the buttock and 0.920 [0.846/0.967] at the calf levels, in experiment A; ICC were 0.873 [0.799/0.923] at the buttock and 0.898 [0.790/0.953] at the calf levels, in experiment B; 0.806 [0.716/0.871] at then buttock level (n = 67) and 0.807 [0.722/0.868] at the calf in experiment C.
Intra-test and test-retest reliability is excellent using the DROP calculation for exercise-tcpO2 investigations.
经皮氧分压（tcpO2）的可靠性会受到皮肤中不可预测的经皮梯度的影响而减弱。我们假设“从休息时的氧压下降（DROP：从各自的起始值减去肢体变化与胸部变化）在运动-tcpO2 研究中会显示出良好到极好的可靠性。
我们在三个不同的实验中进行了测试：在末梢水平的组内测试变异性（实验 A：32 名患者，每个部位 16 名），在胸部水平（实验 B：45 名患者）以及 3 个月内的测试-再测试可重复性（实验 C：67 名患者）。我们用 95%置信区间[下限/上限]计算了组内相关系数（ICC）。ICC 值在 0.60 到 0.749 之间表示良好的一致性。ICC 值大于 0.750 表示极好的一致性。
在实验 A 中，DROP-min 的 ICC 值在臀部为 0.848[0.723/0.935]，在小腿为 0.920[0.846/0.967]；在实验 B 中，臀部为 0.873[0.799/0.923]，小腿为 0.898[0.790/0.953]；在实验 C 中，臀部为 0.806[0.716/0.871]（n=67），小腿为 0.807[0.722/0.868]。
使用 DROP 计算在运动-tcpO2 研究中具有极好的组内和测试-再测试可靠性。
