脑出血中的远程扩散加权成像病变：特征、机制、结局及治疗意义
Remote Diffusion-Weighted Imaging Lesions in Intracerebral Hemorrhage: Characteristics, Mechanisms, Outcomes, and Therapeutic Implications.
作者信息
Xu Xu-Hua, Gao Ting, Zhang Wen-Ji, Tong Lu-Sha, Gao Feng
机构信息
School of Medicine, Zhejiang University, Hangzhou, China.
Department of Neurology, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu, China.
出版信息
Front Neurol. 2017 Dec 15;8:678. doi: 10.3389/fneur.2017.00678. eCollection 2017.
Abstract
Spontaneous intracerebral hemorrhage (ICH) is one of the most fatal form of stroke, with high mortality and disability rate. Small diffusion-weighed imaging lesions are not rare to see in regions remote from the hematoma after ICH and have been generally considered as related with poor outcome. In this review, we described the characteristics of remote ischemic lesions, discussed the possible mechanisms and clinical outcomes of these lesions, and evaluated the potential therapeutic implications.
摘要
自发性脑出血（ICH）是最致命的中风形式之一，具有高死亡率和致残率。在脑出血后远离血肿的区域，小的弥散加权成像病变并不少见，并且通常被认为与不良预后有关。在本综述中，我们描述了远隔缺血性病变的特征，讨论了这些病变的可能机制和临床结果，并评估了潜在的治疗意义。
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2
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3
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4
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