Otti Oliver, Deines Peter, Hammerschmidt Katrin, Reinhardt Klaus
Animal and Plant Sciences, University of Sheffield, Sheffield, United Kingdom.
Animal Population Ecology, Animal Ecology I, University of Bayreuth, Bayreuth, Germany.
Front Immunol. 2017 Dec 18;8:1855. doi: 10.3389/fimmu.2017.01855. eCollection 2017.
During wounding, tissues are disrupted so that bacteria can easily enter the host and trigger a host response. Both the host response and bacterial communication can occur through quorum sensing (QS) and quorum sensing inhibition (QSI). Here, we characterize the effect of wounding on the host-associated bacterial community of the bed bug. This is a model system where the male is wounding the female during every mating. Whereas several aspects of the microbial involvement during wounding have been previously examined, it is not clear to what extent QS and QSI play a role. We find that the microbiome differs depending on mating and feeding status of female bedbugs and is specific to the location of isolation. Most organs of bedbugs harbor bacteria, which are capable of both QS and QSI signaling. By focusing on the prokaryotic quorum communication system, we provide a baseline for future research in this unique system. We advocate the bedbug system as suitable for studying the effects of bacteria on reproduction and for addressing prokaryote and eukaryote communication during wounding.
在受伤过程中，组织会受到破坏，使得细菌能够轻易进入宿主体内并引发宿主反应。宿主反应和细菌间通讯都可通过群体感应（QS）和群体感应抑制（QSI）发生。在此，我们描述了受伤对臭虫宿主相关细菌群落的影响。这是一个模型系统，在每次交配过程中雄性都会弄伤雌性。尽管此前已经研究了受伤过程中微生物参与的几个方面，但尚不清楚群体感应和群体感应抑制在多大程度上发挥作用。我们发现，微生物群落因雌性臭虫的交配和进食状态而异，并且特定于分离的位置。臭虫的大多数器官都含有细菌，这些细菌能够进行群体感应和群体感应抑制信号传导。通过关注原核生物的群体通讯系统，我们为该独特系统的未来研究提供了一个基线。我们提倡将臭虫系统作为研究细菌对繁殖的影响以及解决受伤过程中原核生物与真核生物通讯问题的合适模型。
